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Back Pain

Consensus among musculoskeletal experts for the management of patients with headache by physiotherapists? A delphi study.

Feb 08, 2021

Though a large amount of research on the management of headache has been conducted, the clinical effectiveness of these treatments remains unclear.To reach consensus among international musculoskeleta...

A Clinical Trial of a Video Intervention Targeting Opioid Disposal After General Surgery: A Feasibility Study.

Feb 04, 2021

The opioid epidemic continues and although some initiatives have shown promise in reducing the number of opiates prescribed, few studies have focused on education of general surgery patients about hom...

A randomized controlled trial of the X-Stop interspinous distractor device versus laminectomy for lumbar spinal stenosis with 2-year quality-of-life and cost-effectiveness outcomes.

Feb 04, 2021

Lumbar spinal stenosis (LSS) is a common and debilitating condition that is increasing in prevalence in the world population. Surgical decompression is often standard treatment when conservative measu...

Spine Examination during COVID-19 Pandemic via Video Consultation.

Feb 04, 2021

During the current COVID-19 pandemic video consultations are increasingly common in order to minimize the risk of infection for staff and patients. The aim of this study was to evaluate the feasibilit...

Association of opioid misuse with anxiety and depression: A systematic review of the literature.

Feb 01, 2021

The opioid epidemic is a public health problem associated with a host of negative outcomes. Although clinicians recognize covariation between opioid misuse with anxiety and depressive symptoms and dis...

Multiparametric in vivo analyses of the brain and spine identify structural and metabolic biomarkers in men with adrenomyeloneuropathy.

Feb 01, 2021

Progressive myelopathy causes severe handicap in men with adrenomyeloneuropathy (AMN), an X-linked disorder due to ABCD1 pathogenic variants. At present, treatments are symptomatic but disease-modifyi...

Development of a detailed human neck finite element model and injury risk curves under lateral impact.

Feb 01, 2021

Advanced neck finite element modeling and development of neck injury criteria are important for the design of optimal neck protection systems in automotive and other environments. They are also import...

Expanding access to methadone treatment in Ohio through federally qualified health centers and a chain pharmacy: A geospatial modeling analysis.

Jan 28, 2021

In the United States, methadone provision for opioid use disorder (OUD) occurs at opioid treatment programs (OTPs). Ohio recently enacted a policy to expand methadone administration to Federally Quali...

Isotonitazene: Fatal intoxication in three cases involving this unreported novel psychoactive substance in Switzerland.

Jan 28, 2021

The paper describes the first three deaths reported in Europe involved in isotonitazene consumption, a potent benzimidazole derivate opioid consumed in the recreational drug scene. Isotonitazene powde...

[Effects of complete Freund's adjuvant on autophagy protein expression in rat tuberculous wound model].

Jan 28, 2021

To explore the effects of complete Freund's adjuvant on autophagy protein expression in rat tuberculous wound model. The experimental research method was used. In the first batch, 12 6-week-old male...

LncRNA NEAT1/miR-128-3p/AQP4 axis regulating spinal cord injury-induced neuropathic pain progression.

Dec 31, 2020

Neuropathic pain (NP) is the comorbidity in spinal cord injury(SCI), which is the hardest to cure. Non-coding RNA dysregulations are related to the development of NP. NEAT1(nuclear paraspeckle assembl...

Circumstances of overdose among suburban women who use opioids: Extending an urban analysis informed by drug, set, and setting.

Dec 31, 2020

Opioid overdoses are primarily discussed by the pharmacological properties of the drugs used. Research shows that other factors such as the social/physical environment and the mental/emotional states ...

Influence of endplate size and implant positioning of vertebral body replacements on biomechanics and outcome.

Dec 31, 2020

Spinal stabilization by an anterior vertebral body replacement is frequently used in patients suffering from destroyed vertebral bodies. The aim of this study was to analyse (i) the choice of endplate...

The Impact of NSAID Allergies on Opioid Use Disorder in Back Pain

Nov 02, 2020

The opioid epidemic continues to be a serious public health problem in the United States, with opioid-related overdoses claiming the lives of more than 47,000 Americans annually. Higher opioid dosages...

Therapeutic Ultrasound for Chronic Neck & Low Back Pain

Aug 21, 2020

A multimodal approach is most often necessary to adequately manage chronic nonspecific neck pain and low back pain (LBP). The treatment plan may include medications with differing sites of action, phy...

The Impact of Physical Activity & Sedentary Behavior on Fracture Risk

Jul 05, 2020

Regular physical activity, including lighter-intensity activities, and less sedentary time appear to be associated with a lower risk of fracture in older postmenopausal women. Fracture risk ...

Pandemic Presents New Hurdles, And Hope, For People Struggling With Addiction

Jun 04, 2020

Before Philadelphia shut down to slow the spread of the coronavirus, Ed had a routine: most mornings he would head to a nearby McDonald’s to brush his teeth, wash his face and — when he had th...

Static stretch and dynamic muscle activity induce acute similar increase in corticospinal excitability.

Mar 20, 2020

Even though the acute effects of pre-exercise static stretching and dynamic muscle activity on muscular and functional performance have been largely investigated, their effects on the corticospinal pa...

Iliopsoas Release in Hip Arthroscopy: Assessment of Muscle Atrophy.

Mar 20, 2020

Iliopsoas release is a common procedure for coxa saltans interna of the hip. The possible sequelae from this surgery have not been well studied. The purpose of this study was to determine postoperativ...

Lumbar Puncture Guidance

Mar 09, 2020

Data indicate that nearly 400,000 lumbar punctures (LPs) are performed annually for either diagnostic workup or therapeutic relief in the United States. Regular referral to radiology for assistance ...