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Critical Care General

Early-Onset Neonatal Sepsis 2015 to 2017, the Rise of Escherichia coli, and the Need for Novel Prevention Strategies.

May 05, 2020

Early-onset sepsis (EOS) remains a potentially fatal newborn condition. Ongoing surveillance is critical to optimize prevention and treatment strategies.To describe the current incidence, microbiology...

Burn Infection and Burn Sepsis.

May 05, 2020

Infection is the most common complication and cause of death in patients suffering burn injuries. These patients are susceptible to infection and burn wound sepsis secondary to the alterations in the...

Content analysis of concussion education for coaches of youth and high school sport.

May 05, 2020

: Describe the extent to which concussion education provided to coaches of US high school and youth sport is inclusive of information necessary for them to engage in target behaviors related to the pr...

Temperature-sensitive bone mesenchymal stem cells combined with mild hypothermia reduces neurological deficit in rats of severe traumatic brain injury.

May 05, 2020

To explore the combined influences of temperature-sensitive bone mesenchymal stem cells (tsBMSCs) and mild hypothermia (MH) on neurological function and glucose metabolism in rats with severe traumati...

Traumatic Brain Injury and Posttraumatic Stress Disorder: Comorbid Consequences of War.

May 05, 2020

Scientific literature is reviewed supporting a "consequence of war syndrome (CWS)" in Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn soldiers. CWS constituents include chronic p...

Diagnosis and long-term management of post-traumatic seizures in a white-crowned pionus ().

May 05, 2020

A 13-year-old female white-crowned pionus () was examined because of seizures 22 months after it was treated for a traumatic brain injury (TBI) characterized by vision loss, hemiparesis, nystagmus, ci...

Advanced neuroimaging in traumatic brain injury: an overview.

May 05, 2020

Traumatic brain injury (TBI) is a common condition with many potential acute and chronic neurological consequences. Standard initial radiographic evaluation includes noncontrast head CT scanning to ra...

Diagnosis and Surgical Outcomes of Patients with Anomalous Left Coronary Artery from the Pulmonary Artery: A Single Taiwanese Medical Center Experience.

May 05, 2020

Anomalous left coronary artery from the pulmonary artery (ALCAPA), a very rare congenital cardiac anomaly, is associated with a high mortality rate among infants who are not diagnosed or treated in a ...

Effects of Yixintai Pills on Myocardial Cell Apoptosis in Rats With Adriamycin-Induced Heart Failure.

May 05, 2020

To study the effects of Yixintai pills on myocardial cell apoptosis in rats with adriamycin (ADR)-induced heart failure (HF) and the mechanism of action.Sixty healthy male Wistar rats randomly were di...

Abnormalities in Sodium Current and Calcium Homeostasis as Drivers of Arrhythmogenesis in Hypertrophic Cardiomyopathy.

May 05, 2020

Hypertrophic cardiomyopathy (HCM) is a common inherited monogenic disease with a prevalence of 1/500 in the general population, representing an important cause of arrhythmic sudden cardiac death (SCD)...

Human induced pluripotent stem cells for modelling metabolic perturbations and impaired bioenergetics underlying cardiomyopathies.

May 05, 2020

Normal cardiac contractile and relaxation function are critically dependent on a continuous energy supply. Accordingly, metabolic perturbations and impaired mitochondrial bioenergetics with subsequent...

Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice.

May 05, 2020

Growth differentiation factor (GDF) 11 levels decline with aging. The age-related loss of GDF 11 has been implicated in the pathogenesis of a variety of age-related diseases. GDF11 supplementation rev...

Characterization of a porcine model of atrial arrhythmogenicity in the context of ischaemic heart failure.

May 05, 2020

Atrial fibrillation (AF) is a major healthcare challenge contributing to high morbidity and mortality. Treatment options are still limited, mainly due to insufficient understanding of the underlying p...

The value of myocardial perfusion imaging in screening coronary artery disease before kidney transplantation.

May 05, 2020

The value of myocardial single-photon emission computed tomography (SPECT) in pre-transplant evaluation of kidney transplant recipients is controversial. We assessed whether myocardial SPECT predicts ...

Mitochondrial transplantation ameliorates ischemia/reperfusion-induced kidney injury in rat.

May 01, 2020

No real therapeutic modality is currently available for Acute kidney injury (AKI) and if any, they are mainly supportive in nature. Therefore, developing a new therapeutic strategy is crucial. Mitocho...

No way out: Causes of duodenal and gastric outlet obstruction.

May 01, 2020

Upper gastrointestinal obstruction (UGIO), obstruction occurring at the level of the stomach or duodenum, represents only about 5% of bowel obstructions. As with other bowel obstructions, timely diagn...

Association of Sepsis Diagnosis at Daytime and on Weekdays with Compliance to the 3-Hour Sepsis Treatment Bundles: A Multicenter Cohort Study.

May 01, 2020

Compliance with sepsis bundles is associated with better outcomes, but information to support structural actions that might improve compliance is scarce. Few studies have evaluated bundle compliance i...

Fluid Response Evaluation in Sepsis Hypotension and Shock: A Randomized Clinical Trial.

May 01, 2020

Fluid and vasopressor management in septic shock remains controversial. In this randomized controlled trial, we evaluated the efficacy of dynamic measures (stroke volume change during passive leg rais...

Sepsis survivor mice exhibit a behavioral endocrine syndrome with ventral hippocampal dysfunction.

May 01, 2020

Severe acute stressors are known to trigger mood disorders in humans. Sepsis represents one such stressor, and survivors often suffer long term from psychiatric morbidity. We hypothesized that sepsis ...

Soluble Interleukin-2 Receptor (sIL-2r) Level is a Limited Test for the Diagnosis of Adult Secondary Hemophagocytic Lymphohistiocytosis (HLH).

May 01, 2020

Soluble interleukin-2 receptor (sIL-2r) level is used as a diagnostic tool in hemophagocytic lymphohistiocytosis (HLH). However, evidence supporting its use among adults is inadequate.We conducted a r...

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