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Critical Care General

Risk factors for predicting mortality in elderly patients with COVID-19: a review of clinical data in China.

May 01, 2020

While elderly patients are at high risk of fatality, research concerning COVID-19 has largely been done on clarifying the clinical features. As such, the present work aims to identify risk factors for...

Murine typhus. How does it affect us in the 21st century? The epidemiology of inpatients in Spain (1997-2015).

May 01, 2020

The aim of this study was to analyse the epidemiological impact of murine typhus in patients who required hospitalization in the National Health System (SNS) in Spain between 1997 and 2015.Murine typh...

Serum albumin-mediated strategy for the effective targeting of SARS-CoV-2.

May 01, 2020

Novel coronavirus (NCoV-19), also known as SARS CoV-2, is a pathogen causing an emerging infection that rapidly increases in incidence and geographic range, is associated with the ever-increasing morb...

Containing COVID-19 among 627,386 Persons Contacting with Diamond Princess Cruise Ship Passengers Disembarked in Taiwan: Big Data Analytics.

May 01, 2020

Low infection and case-fatality rate has been so far observed in Taiwan. One of major success is attributed to making a better use of big data analytics in efficient contacting tracing and management ...

Incident Comorbidities, Aging and the Risk of Stroke in 608,108 Patients with Atrial Fibrillation: A Nationwide Analysis.

May 01, 2020

We hypothesized that the change in stroke risk profile between baseline and follow-up may be a better predictor of ischemic stroke than the baseline stroke risk determination using the CHADS-VASc scor...

Comparison of longitudinal change in sST2 vs BNP to predict major adverse cardiovascular events in asymptomatic patients in the community.

May 01, 2020

Biomarker-based preventative and monitoring strategies are increasingly used for risk stratification in cardiovascular (CV) disease. The aim of this study was to investigate the utility of longitudina...

Prevalence and Associated Risk Factors of Sepsis among Neonates Admitted into Neonatal Intensive Care Units of Public Hospitals in Dhaka.

May 01, 2020

To determine the prevalence and associated risk factors of sepsis among neonates admitted into neonatal intensive care units (NICU) of public hospitals in Dhaka.This was a cross-sectional study conduc...

Two Cases of Influenza B Virus-Related Fatal Fulminant Pneumonia Complicated With Infection in China Diagnosed Using Next-Generation Sequencing (2018).

May 01, 2020

Two rare cases of Chinese female patients with influenza B virus infection complicated with both fulminant pneumonia and septicemia caused by Panton-Valentine leukocidin(PVL) positive methicillin-sens...

Rapidly expanding saphenous vein graft myoctic aneurysm causing ST-elevation myocardial infarction: a case report.

May 01, 2020

Mycotic aneurysms of coronary vein grafts are rare and associated with high mortality. They are most commonly a result of surgical or percutaneous intervention, and present with complications includin...

Impact of prehospital antibiotic therapy on septic shock mortality.

May 01, 2020

Septic shock (SS) is associated with high morbidity and mortality rate. Early antibiotic therapy administration in septic patients was shown to reduce mortality but its impact on mortality in a preho...

Frequency and management of maternal infection in health facilities in 52 countries (GLOSS): a 1-week inception cohort study.

May 01, 2020

Maternal infections are an important cause of maternal mortality and severe maternal morbidity. We report the main findings of the WHO Global Maternal Sepsis Study, which aimed to assess the frequency...

Characteristics of Schools with Youth Sports Concussion-Related Educational Policies and Practices.

May 01, 2020

School policies and practices designed to educate athletes, parents, and coaches about youth sports concussions may be a way to reduce concussion risk and improve both the recognition and management o...

Functional Neuroimaging in Psychiatry-Aiding in Diagnosis and Guiding Treatment. What the American Psychiatric Association Does Not Know.

May 01, 2020

While early efforts in psychiatry were focused on uncovering the neurobiological basis of psychiatric symptoms, they made little progress due to limited ability to observe the living brain. Today, we ...

Predicting Concussion Outcome by Integrating Finite Element Modeling and Network Analysis.

May 01, 2020

Concussion is a significant public health problem affecting 1.6-2.4 million Americans annually. An alternative to reducing the burden of concussion is to reduce its incidence with improved protective ...

Immunization with neural-derived peptides increases neurogenesis in rats with chronic spinal cord injury.

May 01, 2020

Immunization with neural-derived peptides (INDP) has demonstrated to be a promising therapy to achieve a regenerative effect in the chronic phase of the spinal cord injury (SCI). Nevertheless, INDP-in...

Does the skull Hounsfield unit predict shunt dependent hydrocephalus after decompressive craniectomy for traumatic acute subdural hematoma?

May 01, 2020

Posttraumatic hydrocephalus affects 11.9%-36% of patients undergoing decompressive craniectomy (DC) after traumatic brain injury and necessitates a ventriculo-peritoneal shunt placement. As bone and a...

The prevalence and importance of frailty in heart failure with reduced ejection fraction - an analysis of PARADIGM-HF and ATMOSPHERE.

May 01, 2020

Frailty, characterized by loss of homeostatic reserves and increased vulnerability to physiological decompensation, results from an aggregation of insults across multiple organ systems. Frailty can be...

Management of low blood pressure in ambulatory heart failure with reduced ejection fraction patients.

May 01, 2020

Low blood pressure is common in patients with heart failure and reduced ejection fraction (HFrEF). While spontaneous hypotension predicts risk in HFrEF, there is only limited evidence regarding the re...

Folic acid affects cardiometabolic, oxidative stress and immunohistochemical parameters in monocrotaline-induced rat heart failure.

May 01, 2020

Heart failure (HF) is one of the major cardiovascular causes of death worldwide. In this study, we explored the effects of folic acid (FA) on cardiometabolic, oxidative stress-biomarker changes and th...

Empagliflozin improves left ventricular diastolic function of db/db mice.

May 01, 2020

Investigation of the effect of SGLT2-inhibition by empagliflozin on left ventricular function in a model of diabetic cardiomyopathy.SGLT2 inhibition is a new strategy to treat diabetes. In the EMPAREG...

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