A 2023 update to the ASCO guidelines focuses on practical assessment and management of age-associated vulnerabilities in older adults undergoing cancer therapy. Given new research regarding the vulnerabilities of older adults undergoing systemic...
Oncology / Hematology
RELEVANT ARTICLES IN Oncology / Hematology
Zanubrutinib-treated CLL Patients: Evaluation of Immunity During Five SARS-CoV-2 Vaccinations
Zanubrutinib-treated CLL Patients: Evaluation of Immunity During Five SARS-CoV-2 Vaccinations
The following is a summary of “Local and Systemic Immunity During Five Vaccinations Against SARS-CoV-2 in Zanubrutinib-Treated Patients With Chronic Lymphocytic Leukemia,” published in the August 2023 issue of Hematology by Andersson et al. Patients with chronic...
Atezolizumab in Combination with Pemetrexed and Carboplatin in Advanced NSCLC with Untreated Brain Metastases
Atezolizumab in Combination with Pemetrexed and Carboplatin in Advanced NSCLC with Untreated Brain Metastases
The following is a summary of "Phase II Trial of Atezolizumab Combined With Carboplatin and Pemetrexed for Patients With Advanced Nonsquamous Non–Small-Cell Lung Cancer With Untreated Brain Metastases," published in the October 2023 issue of Oncology by Nadal, et...
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Examining PLR and NLR as a Prognostic Indicators for Paragangliomas and Pheochromocytomas
Examining PLR and NLR as a Prognostic Indicators for Paragangliomas and Pheochromocytomas
The following is a summary of "Platelet-Lymphocyte and Neutrophil-Lymphocyte Ratios Are Prognostic Markers for Pheochromocytomas and Paragangliomas," published in the September 2023 issue of Endocrinology by Zhong, et al. In recent years, preoperative inflammatory...
Diversity in Early-Phase Cancer Trials Improved Since 2000
Diversity in Early-Phase Cancer Trials Improved Since 2000
TUESDAY, Oct. 3, 2023 (HealthDay News) -- There have been some increases in diversity in early-phase cancer clinical trials since 2000, according to a study presented at the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic...
More Than 75,000 Kaiser Permanente Union Workers Could Strike on Wednesday
More Than 75,000 Kaiser Permanente Union Workers Could Strike on Wednesday
TUESDAY, Oct. 3, 2023 (HealthDay News) -- Health care workers who serve millions of Americans could strike Wednesday if Kaiser Permanente and union workers do not reach an agreement.More than 75,000 members of the Coalition of Kaiser Permanente Unions are poised to...
Zanubrutinib-treated CLL Patients: Evaluation of Immunity During Five SARS-CoV-2 Vaccinations
Zanubrutinib-treated CLL Patients: Evaluation of Immunity During Five SARS-CoV-2 Vaccinations
The following is a summary of “Local and Systemic Immunity During Five Vaccinations Against SARS-CoV-2 in Zanubrutinib-Treated Patients With Chronic Lymphocytic Leukemia,” published in the August 2023 issue of Hematology by Andersson et al. Patients with chronic...
Atezolizumab in Combination with Pemetrexed and Carboplatin in Advanced NSCLC with Untreated Brain Metastases
Atezolizumab in Combination with Pemetrexed and Carboplatin in Advanced NSCLC with Untreated Brain Metastases
The following is a summary of "Phase II Trial of Atezolizumab Combined With Carboplatin and Pemetrexed for Patients With Advanced Nonsquamous Non–Small-Cell Lung Cancer With Untreated Brain Metastases," published in the October 2023 issue of Oncology by Nadal, et...
Examining PLR and NLR as a Prognostic Indicators for Paragangliomas and Pheochromocytomas
Examining PLR and NLR as a Prognostic Indicators for Paragangliomas and Pheochromocytomas
The following is a summary of "Platelet-Lymphocyte and Neutrophil-Lymphocyte Ratios Are Prognostic Markers for Pheochromocytomas and Paragangliomas," published in the September 2023 issue of Endocrinology by Zhong, et al. In recent years, preoperative inflammatory...
Diversity in Early-Phase Cancer Trials Improved Since 2000
Diversity in Early-Phase Cancer Trials Improved Since 2000
TUESDAY, Oct. 3, 2023 (HealthDay News) -- There have been some increases in diversity in early-phase cancer clinical trials since 2000, according to a study presented at the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic...
More Than 75,000 Kaiser Permanente Union Workers Could Strike on Wednesday
More Than 75,000 Kaiser Permanente Union Workers Could Strike on Wednesday
TUESDAY, Oct. 3, 2023 (HealthDay News) -- Health care workers who serve millions of Americans could strike Wednesday if Kaiser Permanente and union workers do not reach an agreement.More than 75,000 members of the Coalition of Kaiser Permanente Unions are poised to...
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CONDITION SPOTLIGHTS
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Genetics & Environmental Interplay in Diabetes & Obesity
Genetics & Environmental Interplay in Diabetes & Obesity
Determinants of obesity and diabetes are strongly linked to genetic and epigenetic variations. With the increasing prevalence of diabetes and obesity, it is imperative to understand the various factors that influence metabolic function in the body, neural pathways,...
Medical Fiction: Ronald and the Vassal’s Vessel
Medical Fiction: Ronald and the Vassal’s Vessel
This is one of a collection of stories that are like “Final Destination” meets “The Monkey’s Paw” (W. W. Jacobs, 1902). As such, they are tragedies more than either mysteries or horror, and would appeal most to readers who enjoy the inexorable pull of a story arc...
What Does Negligence Really Mean?
What Does Negligence Really Mean?
Any discussion with doctors about avoiding liability for malpractice is hampered from the start because “negligence” is a very charged term. It conjures up images of a slipshod and blundering individual and so doctors understandably immediately become resistant....
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Foolish Doctor
Foolish Doctor
"When experts determine that high blood pressure, heart disease and diabetes are actually good for you, you're going to feel awfully foolish!"
Miles You Didn’t Walk
Miles You Didn’t Walk
"You can download an app for your phone that shows how many miles you didn't walk today."
Armchair Exercise
Armchair Exercise
"The handle of your recliner does not qualify as an exercise machine."
BUSINESS OF MEDICINE
Are Physicians Morally Obligated to Assist Patients With Medical Crowdfunding?
Are Physicians Morally Obligated to Assist Patients With Medical Crowdfunding?
Medical crowdfunding is touted for its potential to reach an unlimited number of people, the sum of whose individual donations can help achieve campaign goals for even the most daunting financial asks, such as $2.1 million to cover the cost of Zolgensma. For...
Prioritizing Your Own Well-Being
Prioritizing Your Own Well-Being
I was getting ready to sit down and write a piece on the damage that Robert F. Kennedy Jr has done to healthcare and the safety of our children, as well as his recent inflammatory racist/antisemitic comments. It was going to be an essay about how physicians need to...
How Physicians Can Prepare for a Potential Economic Depression
How Physicians Can Prepare for a Potential Economic Depression
To curb inflation and turbulent markets, the US Federal Reserve has marked 2023 with rising interest rates. This economic climate has many financial experts apprehensive about a possible recession. According to Bankrate’s Fourth-Quarter Economic Indicator poll of...
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