Oct 15, 2020

Diabetes mellitus (DM) often causes ocular disorders leading to vision loss. Metformin is commonly prescribed for type 2 diabetes. This study assessed the effect of metformin on hyperglycemic histopat...

Oct 15, 2020

NETosis, a novel form of neutrophil-related cell death, acts as a major regulator of diabetes and diabetes-associated complications. In this review, we show that the extrusion of neutrophil extracellu...

Oct 15, 2020

Ultrasound (US) assisted drug delivery is receiving interest in treating posterior eye diseases such as diabetic retinopathy (DR) due to its ability to maximise drug penetration into difficult to reac...

Oct 15, 2020

Retinitis pigmentosa (RP) is a collection of heterogenous genetic retinal disorders resulting in cumulative retinal deterioration involving progressive loss of photoreceptors and eventually in total b...

Oct 15, 2020

Provide outcomes up to 12 months post-surgically for sequential canaloplasty and trabeculotomy with the OMNI surgical system (OMNI) in pseudophakic patients with mild to moderate open-angle glaucoma (...

Oct 12, 2020

Voltage-gated Ca1 and Ca2 Ca channels are comprised of a pore-forming a1 subunit (Ca1.1-1.4, Ca2.1-2.3) and auxiliary β (β) and αδ (αδ-1-4) subunits. The properties of these channels vary with d...

Oct 12, 2020

The multifactorial pathogenesis and interrelationship of blepharitis, meibomian gland dysfunction and dry eye disease poses challenges to any therapeutic approach. Current treatments are mostly pallia...

Oct 12, 2020

The purposes of this study were to assess the reproducibility of a novel standardized technique for capturing corneal subbasal nerve plexus images with in vivo corneal confocal microscopy and to compa...

Oct 12, 2020

The lacrimal functional unit (LFU) regulates tear production, composition, distribution and clearance to maintain a stable protective tear layer that is essential for maintaining corneal epithelial he...

Oct 12, 2020

To evaluate the potential of lactoferrin (Lf) as a diagnostic biomarker for ocular diseases using a meta-analytic approach.All original studies reporting an estimate of the average Lf concentration in...

Oct 12, 2020

Transcorneal electrical stimulation (TES) is a novel treatment approach for patients with retinitis pigmentosa (RP). The aim of our study was to observe changes in optical coherence tomography angiogr...

Oct 12, 2020

To compare intraocular pressure (IOP) control before and during the first year after secondary intraocular lens (IOL) implantation in children.This was a retrospective chart review of children who rec...

Oct 12, 2020

Paclitaxel (PTX) is an antineoplastic drug widely used in treatments for ovarian, breast, and small-cell lung cancer. Although ocular effects associated with PTX have been previously described, very f...

Oct 12, 2020

Deep learning (DL), a subset of artificial intelligence (AI) based on deep neural networks, has made significant breakthroughs in medical imaging, particularly for image classification and pattern rec...

Oct 12, 2020

 This study aimed to profile the cytokine/chemokine response from day 0 to 7 in infants (≥36 weeks of gestational age) with neonatal encephalopathy (NE) and to explore the association with long-te...

Oct 08, 2020

Neovascular retinal degeneration is a leading cause of blindness in advanced countries. Anti-vascular endothelial growth factor (VEGF) drugs have been used for neovascular retinal diseases; however, a...

Oct 08, 2020

Nonsurgical cosmetic procedures, including injection procedures, are among the fastest growing medical procedures. In 2018, botulinum toxin and hyaluronic acid injections were the two most common nons...

Oct 08, 2020

Goblet cells (GCs) in the conjunctiva are specialized epithelial cells producing mucins on the ocular surface. GCs play important roles in maintaining homeostasis of the ocular surface, and GC dysfunc...

Oct 08, 2020

Human tear is a biological fluid rich in lipids that is increasingly collected in clinical and biological research. The repertoire of small lipids or lipid mediators (often termed eicosanoids or oxyli...

Oct 08, 2020

Endocrine disrupting chemicals (EDCs) are a group of chemical compounds that present a considerable public health problem due to their pervasiveness and associations with chronic diseases. EDCs can in...