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Ophthalmology General

Meibomian gland dysfunction is the primary determinant of dry eye symptoms: Analysis of 2346 patients.

Jul 20, 2020

To determine relative contributions of various ocular surface clinical signs and predisposing factors to the magnitude of dry eye symptoms.Clinical audit data were prospectively collected for newly re...

Central retinal artery occlusion as a post-transfusion complication of red blood cells.

Jul 16, 2020

A 32-year-old woman presented with a history of uterine myomatosis and repeated bleeding for 6 months. This produced a haemoglobin concentration of 6.5 g/dL, with a requirement for a red blood cell t...

MicroRNA-148a-3p alleviates high glucose-induced diabetic retinopathy by targeting TGFB2 and FGF2.

Jul 16, 2020

Diabetic retinopathy (DR), a common complication of type 1 or type 2 diabetes mellitus, has become the leading cause of blindness among adults in working age. The dysregulation of microRNA has been re...

Cataract Surgery Destabilises Temporary the Tear Film of the Ocular Surface.

Jul 16, 2020

Symptoms due to dry eye in the form of keratoconjunctivitis sicca (KCS) are often seen after cataract surgery. We investigated the influence of cataract surgery on tear film stability on the ocular su...

Rete ridges in eyelid margin and inflammatory cytokines in meibomian gland dysfunction associated with dry eye symptom.

Jul 16, 2020

To evaluate the morphology and function of rete ridges in eyelid margin and inflammatory cytokines in meibomian gland dysfunction (MGD) associated with dry eye symptom.A total of 63 subjects with OSDI...

Visualization of micro-neuromas by using in vivo confocal microscopy: An objective biomarker for the diagnosis of neuropathic corneal pain?

Jul 16, 2020

The diagnosis of neuropathic corneal pain (NCP) is challenging, as it is often difficult to differentiate from conventional dry eye disease (DED). In addition to eye pain, NCP can present with similar...

Effects of rhaponticin on retinal oxidative stress and inflammation in diabetes through NRF2/HO-1/NF-κB signalling.

Jul 16, 2020

Oxidative stress and inflammation have long been considered to be responsible for the development and progression of diabetic retinopathy. On the other hand, rhaponticin (RN) has received scientific a...

Choroidal differences between spectral and swept-source domain technologies.

Jul 16, 2020

To assess differences in healthy eyes in volume (CV) and choroidal thicknesses (CT) across all macular Early Treatment Diabetic Retinopathy Study (ETDRS) areas measured by swept source (SS)-OCT and sp...

Altered Red blood cell deformability - A novel hypothesis for retinal microangiopathy in diabetic retinopathy.

Jul 16, 2020

Impaired red blood cell (RBC) deformability impedes tissue perfusion. This study aims to investigate RBC biomechanics in type 2 diabetes mellitus (DM) patients with different grades of diabetic retino...

Understanding metabolism related differences in ocular efficacy of MGV354.

Jul 16, 2020

was being developed as a novel ocular therapy for lowering of intraocular pressure, a key modifiable risk factor for glaucoma. is an activator of soluble guanylate cyclase, an enzyme known to be inv...

VARIABILITY OF VISION HEALTH RESPONSES ACROSS MULTIPLE NATIONAL SURVEY IN THE UNITED STATES.

Jul 16, 2020

Lay the groundwork for future survey validation and harmonization efforts by comparing prevalence rates of self-reported visual impairment (VI) and blindness measured across federally-funded national ...

Short-Term and Long-Term Variability of Intraocular Pressure Measured with an Intraocular Telemetry Sensor in Patients with Glaucoma.

Jul 16, 2020

To evaluate the short- and long-term variability of intraocular pressure (IOP) in eyes with primary open-angle glaucoma (POAG).Twenty-two patients who had previously been implanted with a sulcus based...

Impact of Standardized Prescribing Guidelines on Postoperative Opioid Prescriptions after Ophthalmic Surgery.

Jul 16, 2020

To determine the effect of implementing standardized opioid prescribing guidelines on prescription patterns for acute pain after ophthalmic surgery in opioid-naïve patients.Quality improvement study....

BRACHYTHERAPY OF CHOROIDAL MELANOMAS LESS THAN 10 MM IN LARGEST BASAL DIAMETER Comparison of 10-mm and 15-mm Ruthenium Plaques.

Jul 13, 2020

To compare tumor control, vision, and complications between patients with a choroidal melanoma <10 mm in largest basal diameter (LBD) irradiated with 10-mm or 15-mm ruthenium plaques.Retrospective ...

[Effect of needle-knife as adjunctive therapy on dry eye syndrome].

Jul 13, 2020

To observe the clinical effect of needle-knife at cervical spine area as adjunctive therapy on dry eye syndrome.A total of 84 patients with dry eye syndrome were randomized into 3 groups, named group ...

Importance of tear volume for positivity of tear matrix metalloproteinase-9 immunoassay.

Jul 13, 2020

The tear matrix metalloproteinase-9 (MMP-9) immunoassay (Inflammadry) exhibits variable results in dry eye (DE) patients. We investigated if the tear volume in DE patients affects the results of MMP-9...

Sight-threatening Complication of Cicatricial Ectropion in a Patient with Lamellar Ichthyosis - Case Report.

Jul 13, 2020

We report a case of lamellar ichthyosis and sight-threatening complications of cicatricial ectropion in an adult male patient which was surgically managed with tectonic penetrating keratoplasty. We pr...

Topographic analysis of retinal and choroidal microvasculature according to diabetic retinopathy severity using optical coherence tomography angiography.

Jul 13, 2020

To investigate the topographic changes in the retinal capillary plexus and the choriocapillaris according to the severity of diabetic retinopathy (DR) using optical coherence tomography angiography (O...

Gene Therapy Intervention in Neovascular Eye Disease: A Recent Update.

Jul 13, 2020

Aberrant growth of blood vessels (neovascularization) is a key feature of severe eye diseases that can cause legal blindness, including neovascular age-related macular degeneration (nAMD) and diabetic...

Outcomes by Baseline Choroidal Neovascularization Features in Age-Related Macular Degeneration: A Post Hoc Analysis of the VIEW Studies.

Jul 13, 2020

To assess the influence of baseline choroidal neovascularization (CNV) features on visual change and fluid resolution following anti-vascular endothelial growth factor (anti-VEGF) treatment of eyes wi...

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