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Ophthalmology General

Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status.

Aug 13, 2020

Few reports have explored the possibility of involvement of non-inflammatory factors in lacrimal hyposecretion in Sjögren's syndrome (SS). RNA-seq analysis revealed that only 4 genes, including argin...

Controlled differential evolution based detection of neovascularization on optic disc using support vector machine.

Aug 13, 2020

The severe stage of Diabetic Retinopathy (DR) is characterized by the growth of new blood vessels which is called Neovascularization (NV). The abnormally grown blood vessels on the disc are breakable ...

Of neurons and pericytes: The neuro-vascular approach to diabetic retinopathy.

Aug 13, 2020

Diabetic retinopathy (DR) is a frequent complication of diabetes mellitus and an increasingly common cause of visual impairment. Blood vessel damage occurs as the disease progresses, leading to ischem...

Level of hormones in menopause in relation to diabetic retinopathy among type 2 diabetic women.

Aug 13, 2020

Hormonal transition among middle-aged women with type 2 diabetes may exert an impact in the development of diabetic retinopathy (DR). In this cross-sectional study, we aimed to assess the levels of es...

[Diagnosis and prediction of the course of primary open-angle glaucoma by the level of local cytokines].

Aug 13, 2020

Glaucoma is the leading cause of irreversible blindness in all countries and is expected to increase in patients with this pathology in the coming years. Currently, the development of the disease is a...

Sociodemographic Factors Influencing Rhegmatogenous Retinal Detachment Presentation and Outcome.

Aug 13, 2020

The impact of sociodemographic factors on the presentation and outcomes of rhegmatogenous retinal detachment (RRD) in the United States have not been described. We analyzed the impact of these factors...

Impact of the Support, Educate, Empower (SEE) personalized glaucoma coaching program pilot study on eye drop instillation technique and self-efficacy.

Aug 13, 2020

To assess the Support, Educate, Empower (SEE) personalized glaucoma coaching program impact on 1) eye drop instillation technique and 2) eye drop instillation self-efficacy.A prospective pre-post pilo...

DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - RNA Accumulation versus miRNA Dysregulation.

Aug 10, 2020

DICER1 deficiency in the retinal pigment epithelium (RPE) was associated with the accumulation of transcripts and implicated in geographic atrophy (GA), a form of age-related macular degeneration (AM...

Automated identification of retinopathy of prematurity by image-based deep learning.

Aug 10, 2020

Retinopathy of prematurity (ROP) is a leading cause of childhood blindness worldwide but can be a treatable retinal disease with appropriate and timely diagnosis. This study was performed to develop a...

A Review of Dry Eye Questionnaires: Measuring Patient-Reported Outcomes and Health-Related Quality of Life.

Aug 10, 2020

Dry eye disease (DED) is among the most common eye diseases and is becoming increasingly prevalent. Its symptoms cause a long-term decline in patients' health-related quality of life (HRQL). Inconsist...

Optical Quality and Tear Film Analysis Before and After Intranasal Stimulation in Patients with Dry Eye Syndrome.

Aug 10, 2020

To evaluate the optical quality and tear film quality in patients with dry eye syndrome (DES) before and after using an intranasal neurostimulation device to stimulate tear production.Cross-sectional ...

Intense pulsed light for the treatment of Meibomian gland dysfunction: A systematic review and meta-analysis.

Aug 10, 2020

Meibomian gland dysfunction (MGD) is frequently encountered by eye care practitioners. It is characterised by obstruction of the Meibomian glands and/or alterations in the consistency of glandular sec...

The Evolution of Diabetic Retinopathy Screening Programmes: A Chronology of Retinal Photography from 35 mm Slides to Artificial Intelligence.

Aug 10, 2020

As a third of people with diabetes mellitus (DM) will suffer the microvascular complications of diabetic retinopathy (DR) and therapeutic options can effectively prevent visual impairment, systematic ...

STEAP4 Inhibits HIF-1α/PKM2 Signaling and Reduces High Glucose-Induced Apoptosis of Retinal Vascular Endothelial Cells.

Aug 10, 2020

Diabetic retinopathy (DR) is a vascular lesion induced by high glucose. STEAP4 is an indispensable membrane protein, which is closely related to hyperglycemic-induced cell inflammation and injury, whi...

Optical Coherence Tomography Angiography in Neurodegenerative Diseases: A Review.

Aug 10, 2020

Optical coherence tomography angiography (OCT-A) has emerged as a novel, fast, safe and non-invasive imaging technique of analyzing the retinal and choroidal microvasculature in vivo. OCT-A captures m...

Better olfactory performance and larger olfactory bulbs in a mouse model of congenital blindness.

Aug 10, 2020

It is well established that early blindness results in enhancement of the remaining non-visual sensory modalities accompanied by functional and anatomical brain plasticity. While auditory and tactile ...

Systemic Alpha1-Adrenoceptor Antagonists and Increased Risk of Open-Angle Glaucoma: A Nationwide Population-Based Cohort Study.

Aug 10, 2020

To examine the risk of open-angle glaucoma (OAG) among patients receiving alpha1-adrenoceptor (α1-AR) antagonists for lower urinary tract symptoms (LUTS).This was a nationwide, population-based, retr...

Short-Term Changes in the Photopic Negative Response Following Intraocular Pressure Lowering in Glaucoma.

Aug 10, 2020

To evaluate the short-term changes in inner retinal function using the photopic negative response (PhNR) after intraocular pressure (IOP) reduction in glaucoma.Forty-seven participants with glaucoma w...

Malpractice Litigation in Ophthalmic Trauma.

Aug 10, 2020

To report and analyze the causes and outcomes of malpractice litigation in ophthalmic trauma.The Westlaw database was reviewed for ophthalmology litigation in the United States between 1930 and 2014. ...

Binocular Visual Function in a Pre-Presbyopic Patient with Uniocular Cataract Undergoing Cataract Surgery with a Multifocal Intraocular Lens.

Aug 10, 2020

An increasing number of pre-presbyopic patients are undergoing uniocular cataract extraction. We aim to compare the binocular status of subjects with uniocular cataracts, implanted either with a multi...

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