Feb 17, 2021

Patients with type 2 diabetes have a high risk of developing chronic kidney disease. We examined the effects of semaglutide on kidney function and safety in a large, broad type 2 diabetes population. ...

Feb 17, 2021

The melanocortin 4 receptor (MC4R), a component of the leptin–melanocortin pathway, plays a part in body weight regulation. Severe early-onset obesity can be caused by biallelic variants in genes th...

Feb 16, 2021

Patients with type 2 diabetes and atherosclerotic cardiovascular disease are at high clinical risk. We assessed the effect of the sodium-glucose co-transporter-2 inhibitor, empagliflozin, on total car...

Feb 16, 2021

The pancreas is small and irregular in shape in people with type 2 diabetes. If these abnormalities are caused by the disease state itself rather than being a predisposing factor, remission of type 2 ...

Feb 16, 2021

Men who are overweight or obese frequently have low serum testosterone concentrations, which are associated with increased risk of type 2 diabetes. We aimed to determine whether testosterone treatment...

Feb 16, 2021

Dapagliflozin reduces the risk of kidney failure and heart failure in patients with chronic kidney disease. We aimed to investigate the effects of dapagliflozin on kidney, cardiovascular, and mortalit...

Feb 16, 2021

PPGL (Pheochromocytoma or paraganglioma) in pregnant women might cause intense complexity and death because of excess related catecholamine. The purpose of this study was to determine factors correlat...

Feb 11, 2021

The objective of this study was to determine the correlations between clinical outcomes of spinal surgery to correct adult spinal deformity (ASD) including mechanical complications and coronal malalig...

Feb 11, 2021

Cervical spine injuries commonly occur during athletic play, and such injuries carry significant risk for adverse sequelae if not properly managed. Although guidelines for managing return to play exis...

Feb 11, 2021

This is a prospective, stratified randomized, multicenter, 4-year follow-up study. The authors aimed to evaluate the long-term clinical efficacy and safety of CaO-SiO2-P2O5-B2O3 glass ceramics (BGS-7)...

Feb 11, 2021

The objective of this study was to determine if the use of image-guided navigation offers a clinically significant advantage over fluoroscopy-assisted pedicle screw and non-navigated screw placement i...

Feb 11, 2021

To determine the improvement of clinical outcomes in Workers’ Compensation (WC) patients compared with non-WC patients utilizing Patient-reported Outcome Measurement Information System Physical Func...

Feb 10, 2021

To determine if the presence of diabetes mellitus as comorbidity is associated with complications, inpatient length of stay, or direct hospital costs after minimally invasive transforaminal lumbar int...

Feb 10, 2021

To describe a novel reconstruction strategy using a T-shaped titanium mesh cage with posterior cervical screw-rod fixation after total spondylectomy of axis tumors. Instability of the upper cervical s...

Feb 10, 2021

A retrospective subgroup analysis of a prospective observational study was carried out. Patients’ baseline characteristics may influence the clinical outcomes after minimally invasive lumbar interbo...

Feb 10, 2021

To evaluate the correlation between preoperative radiologic degree and the postoperative prognosis in lumbar foraminal stenosis (LFS) patients who required decompression. There have been only a few st...

Feb 10, 2021

The objective of this study was to assess the risk factors for deformity progression after scoliosis correction surgery in spinal muscular atrophy (SMA) patients. Moderate residual postoperative scoli...

Feb 09, 2021

Researchers conducted this study to describe current co-cyprindiol prescribing in an extensive, rural general practice. Researchers conducted this study to specifically investigate whether co-cyprindi...

Feb 09, 2021

Increasing numbers of women having an early medical abortion choose to go home soon after misoprostol administration to expel the pregnancy at home, rather than remain upon the hospital premises. Howe...

Feb 09, 2021

The introduction of LBC for cervical screening in the UK has enabled research into human papillomavirus as an adjunct to screening. The authors explored women's views on remnant LBC samples for sexual...