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Critical Care General

National Imaging Trends in Pediatric Traumatic Brain Injury and Hydrocephalus.

Apr 20, 2020

CT reduction in favor of rapid sequence MRI to decrease pediatric radiation exposure has varied across institutions. We aim to understand national trends in CT and rapid sequence MRI usage, as well as...

Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders.

Apr 20, 2020

Investigations of Alzheimer's disease (AD), traumatic brain injury (TBI), and related brain disorders have provided extensive evidence for involvement of cathepsin B, a lysosomal cysteine protease, in...

Characteristics and outcome of severe traumatic brain injuries based on occupational status.

Apr 20, 2020

The association of TBI with socioeconomic characteristics of patients has not been studied extensively. The objective of this study was to analyse the differences in injury characteristics and outcome...

High-sensitivity cardiac troponin T 30 days all-come mortality in patients with acute heart failure. A Propensity Score-Matching Analysis Based on the EAHFE Registry. TROPICA4 Study.

Apr 20, 2020

Acute heart failure (AHF) patients with high troponin levels have a worse prognosis. High-sensitive troponin T (hs-TnT) has been used as a tool to stratify prognosis in many scales but always as a qua...

Predicting Functional Outcome Based on Linked Data After Acute Ischemic Stroke: S-SMART Score.

Apr 20, 2020

Prediction of outcome after stroke may help clinicians provide effective management and plan long-term care. We aimed to develop and validate a score for predicting good functional outcome available f...

Extracellular matrix-based biomaterials for cardiac regeneration and repair.

Apr 20, 2020

The spectrum of ischemic heart diseases, encompassing acute myocardial infarction to heart failure, represents the leading cause of death worldwide. Although extensive progress in cardiovascular diagn...

Prognosis of patients eligible for dapagliflozin in acute heart failure.

Apr 20, 2020

Dapagliflozin, a sodium-glucose cotransporter 2 inhibitor, was shown in the DAPA-HF study to reduce the risk of worsening heart failure or death in symptomatic patients with left ejection fraction < 4...

Comorbidities in the Elderly and Their Possible Influence on Vaccine Response.

Apr 20, 2020

The following chapter is focused on the impact of comorbidities on the effectiveness of vaccination in older persons. Relevant comorbidities are cardiovascular diseases like hypertension, coronary art...

Midregional pro atrial natriuretic peptide: a novel important biomarker for noise annoyance-induced cardiovascular morbidity and mortality?

Apr 20, 2020

Environmental noise exposure has been associated with increased cardiovascular morbidity and mortality. Recently, noise annoyance was shown to induce atrial fibrillation, which was accompanied by sign...

Prolonged Therapeutic Effects of Photoactivated Adipose-derived Stem Cells following Ischemic Injury.

Apr 20, 2020

Adipose-derived stem cells (ASCs) therapies are emerging as a promising approach to therapeutic angiogenesis. Therapeutic persistence and reduced primitive stem cell function following cell delivery...

Perioperative and Long-Term Outcomes after Percutaneous Thrombectomy of Arteriovenous Dialysis Access Grafts Outcomes after Percutaneous Graft Thrombectomy.

Apr 15, 2020

Maintenance of functional arteriovenous dialysis grafts (AVG) is difficult secondary to low primary patency, need for re-interventions, and limited alternative dialysis access options. We assessed our...

Optogenetic translocation of protons out of penumbral neurons is protective in a rodent model of focal cerebral ischemia.

Apr 15, 2020

Intracellular acidosis in the ischemic penumbra can contribute to further cell death, effectively enlarging the infarct core. Restoring the acid-base balance may enhance tissue survivability after cer...

Conserved function of zebrafish (Danio rerio) Gdf15 as a sepsis tolerance mediator.

Apr 15, 2020

GDF15 is frequently detected in patients suffering from various diseases, especially those associated with pro-inflammatory processes and/or metabolic disorders. Accordingly, sepsis, whose major compl...

Genetic evolution of invasive emm28 Streptococcus pyogenes strains and significant association with puerperal infections in young women, Finland.

Apr 15, 2020

Streptococcus pyogenes or group A streptococcus (GAS) is a human specific pathogen that annually infects over 700 million individuals. GAS strains of type emm28 are an abundant cause of invasive infec...

Presentation and outcome of suspected sepsis in a high-HIV burden, high antiretroviral coverage setting.

Apr 15, 2020

To define sepsis syndromes in high-HIV burden settings in the antiretroviral therapy (ART) era.We characterized a prospective cohort of adults presenting to a tertiary emergency department in Harare, ...

Friend turned foe: A curious case of disrupted endosymbiotic homeostasis promoting the Warburg effect in sepsis.

Apr 15, 2020

Sepsis is a grievous health concern with limited understanding of its precise etiology. Although studies on sepsis have implicated the Warburg effect (mitigation of mitochondrial oxidative phosphoryla...

COVID-19 pneumonia manifestations at the admission on chest ultrasound, radiographs, and CT: single-center study and comprehensive radiologic literature review.

Apr 15, 2020

To investigate the imaging features of emerging COVID-19 pneumonia on chest ultrasound (US), radiographs (CXR) and computed tomography (CT) examinations performed at admission and to provide a compreh...

Investigating the cases of novel coronavirus disease (COVID-19) in China using dynamic statistical techniques.

Apr 15, 2020

The initial investigation by local hospital attributed the outbreak of the novel coronavirus disease (COVID-19) to pneumonia with unknown cause that appeared like the 2003 severe acute respiratory syn...

COVID-19 in the perioperative period of lung resection: a brief report from a single thoracic surgery department in Wuhan, China.

Apr 15, 2020

Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and has subsequently spread worldwide. Clinical information on patients contracted with s...

A Rational Use of Clozapine Based on Adverse Drug Reactions, Pharmacokinetics, and Clinical Pharmacopsychology.

Apr 15, 2020

Using Richardson and Davidson's model and the sciences of pharmacokinetics and clinical pharmacopsychology, this article reviewed the: (1) poor life expectancy associated with treatment-resistant schi...

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