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Stroke

Serum or Plasma for Quantification of Direct Oral Anticoagulants?

Jan 24, 2022

Direct oral anticoagulants (DOACs) are increasingly replacing vitamin K antagonists for prevention of stroke in patients with atrial fibrillation, partly owing to the lack of a need for routine monito...

Investigating the structure-function relationship of the corticomotor system early after stroke using machine learning.

Jan 10, 2022

Motor outcomes after stroke can be predicted using structural and functional biomarkers of the descending corticomotor pathway, typically measured using magnetic resonance imaging and transcranial mag...

Therapeutic effect of Danhong injection on diabetic patients with cerebral infarction and its influence on vascular endothelial function and hemodynamics.

Dec 06, 2021

To investigate the therapeutic effect of Danhong injection on diabetic patients with cerebral infarction and its influence on vascular endothelial function and hemodynamic level. A total of 100 diabet...

Parameter estimation for closed-loop lumped parameter models of the systemic circulation using synthetic data.

Nov 15, 2021

Physics-based models can be applied to describe mechanisms in both health and disease, which has the potential to accelerate the development of personalized medicine. The aim of this study was to inve...

Independent effects of amyloid and vascular markers on long-term functional outcomes: An 8-year longitudinal study of subcortical vascular cognitive impairment.

Nov 01, 2021

Subcortical vascular cognitive impairment (SVCI) is characterized by the presence of cerebral small vessel disease (CSVD) markers. Some SVCI patients also show Alzheimer's disease and cerebral amyloid...

Etiologies and Mechanisms of Ischemic Stroke Associated with Sexual Intercourse: A Literature Review.

Oct 18, 2021

Exposure to some special events, also called stroke triggers, can precipitate the onset of ischemic stroke (IS). Previous studies have presented preliminary hypotheses about sexual intercourse as a tr...

Predictors of Infarction in Tuberculous Meningitis in Indian Patients.

Sep 20, 2021

Stroke is a devastating complication of tuberculous meningitis (TBM) and is an important determinant of its outcome. We propose a model which would help to predict development of infarction or cerebro...

Pathway-specific cortico-muscular coherence in proximal-to-distal compensation during fine motor control of finger extension after stroke.

Aug 26, 2021

Proximal-to-distal compensation is commonly observed in upper extremity(UE) after stroke, mainly due to the impaired fine motor control in hand joints. However, little is known on its related neural r...

Large Vessel Occlusion Prediction in the Emergency Department with National Institutes of Health Stroke Scale Components: A Machine Learning Approach.

Aug 19, 2021

To determine the feasibility of using a machine learning algorithm to screen for large vessel occlusions (LVO) in the Emergency Department (ED).A retrospective cohort of consecutive ED stroke alerts a...

Investigating the "Weekend Effect" on Outcomes of Patients Undergoing Endovascular Mechanical Thrombectomy for Ischemic Stroke.

Aug 12, 2021

With growing evidence of its efficacy for patients with large-vessel occlusion (LVO) ischemic stroke, the use of endovascular thrombectomy (EVT) has increased. The "weekend effect," whereby patients p...

A clinical-in silico study on the effectiveness of multipoint bicathodic and cathodic-anodal pacing in cardiac resynchronization therapy.

Aug 02, 2021

Up to one-third of patients undergoing cardiac resynchronization therapy (CRT) are nonresponders. Multipoint bicathodic and cathodic-anodal left ventricle (LV) stimulations could overcome this clinica...

Differences in the platelet mRNA landscape portend racial disparities in platelet function and suggest novel therapeutic targets.

Jul 15, 2021

The African American (AA) population displays a 1.6 to 3-fold higher incidence of thrombosis and stroke mortality compared to European Americans (EA). Current anti-platelet therapies target the ADP-me...

Risk Factors and Mortality for Atypical Presentation of COVID-19 Infection in Hospitalized Patients - Lessons From the Early Pandemic.

Jul 15, 2021

To assess the clinical epidemiology and outcomes of patients hospitalized with COVID-19 who did not experience fever and cough during the early pandemic.Retrospective cohort of all patients admitted d...

Effects of Dual Transcranial Direct Current Stimulation and Modified Constraint-Induced Movement Therapy to Improve Upper-Limb Function after Stroke: A Double-Blinded, Pilot Randomized Controlled Trial.

Jul 15, 2021

Dual transcranial direct current stimulation (dual tDCS) can be combined with stroke rehabilitation interventions to promote excitatory changes in the cerebral cortex.To investigate how the combined i...

Heart rate variability predicts decline in sensorimotor rhythm control.

Jul 08, 2021

Voluntary control of sensorimotor rhythms (SMR, 8-12 Hz) can be used for brain-computer interface (BCI)-based operation of an assistive hand exoskeleton, e.g., in finger paralysis after stroke. To gai...

Blood Pressure Control in Acute Stroke: Labetalol or Nicardipine?

Jul 05, 2021

To assess the safety and efficacy of continuous infusion (CIV)-labetalol compared to -nicardipine in controlling blood pressure (BP) in the acute stroke setting.Patients were eligible if they had a di...

Metabolic abnormality in acute stroke-like lesion and its relationship with focal cerebral blood flow in patients with MELAS: Evidence from proton MR spectroscopy and arterial spin labeling.

Jul 01, 2021

Our purpose is to detect the metabolic alterations in acute stroke-like lesions (SLLs) and further investigate the correlations between metabolic concentrations and focal cerebral blood flow in patien...

Myoelectric analysis of upper-extremity muscles during robot-assisted bilateral wrist flexion-extension in subjects with poststroke hemiplegia.

Jun 28, 2021

Muscle co-contraction during the execution of motor tasks or training is common in poststroke subjects. EMG-derived muscular activation indexes have been used to evaluate muscle co-contractions during...

Characteristics, Management, and Case-Fatality of Patients Hospitalized for Stroke with a Diagnosis of COVID-19 in France.

Jun 28, 2021

COVID-19 was found to be associated with an increased risk of stroke. This study aimed to compare characteristics, management, and outcomes of hospitalized stroke patients with or without a hospital d...

Lesion loci of impaired affective prosody: A systematic review of evidence from stroke.

Jun 14, 2021

Affective prosody, or the changes in rate, rhythm, pitch, and loudness that convey emotion, has long been implicated as a function of the right hemisphere (RH), yet there is a dearth of literature ide...