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Ophthalmology General

A sialidosis type I cohort and a quantitative approach to multimodal ophthalmic imaging of the macular cherry-red spot

Nov 23, 2020

The study was done to describe the ophthalmologic findings on the largest cohort of patients with sialidosis type I due to deficiency of the lysosomal sialidase, NEU1 and to introduce a quantitative n...

Blindness short after treatment of acute primary angle closure in China

Nov 23, 2020

The study was done to explore the risk factors associated with blindness after treatment of APAC, and to identify the critical time window to decrease the rate of blindness. 1030 consecutive subjects...

Proposal and validation of a new grading system for pterygium (SLIT2)

Nov 23, 2020

The study was done to propose and validate a new pterygium grading system based on slit-lamp evaluation. 217 patients with pterygium were included. All patients underwent slit-lamp examination, and s...

The effect of posterior vitreous detachment on aflibercept response in diabetic macular oedema

Nov 23, 2020

The study was done to investigate the effect of posterior vitreous detachment (PVD) on aflibercept response in treatment-naïve diabetic macular oedema (DME). A retrospective cohort study.150 treatme...

Effects of congenital ptosis on the refractive development of eye and vision in children.

Nov 23, 2020

To investigate the influence of unilateral congenital ptosis on the development of the eye and vision in children.In this prospective observational study, 41 patients with unilateral congenital ptosis...

Myopia progression varies with age and severity of myopia.

Nov 23, 2020

To investigate annual myopia progression in individuals from South Indian states across different age groups, and its association with age of onset and severity of myopia.This retrospective study incl...

Consistency between optical coherence tomography and humphrey visual field for evaluating glaucomatous defects in high myopic eyes.

Nov 23, 2020

The study is to investigate the influence of high myopia on the consistency between optical coherence tomography (OCT) and visual field in primary open-angle glaucoma (POAG).We enrolled 37 patients wi...

A randomised clinical trial of multifocal contact lenses and contact lens discomfort.

Nov 23, 2020

To determine how multifocal contact lenses affect contact lens discomfort.This randomised, participant-masked, crossover clinical trial fitted 84 uncomfortable soft contact lens wearers (30-40 years ...

Esculetin protects human corneal epithelial cells from oxidative stress through Nrf-2 signaling pathway.

Nov 23, 2020

Dry eye formation often originates from oxidative damage to the ocular surface, which can be caused by external environment or internal pathologic factors. Esculetin (6, 7-dihydroxycoumarin) is a natu...

End of Study Results for the Ladder Phase 2 Trial of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration.

Nov 23, 2020

To report the end of study results from the Ladder clinical trial of the Port Delivery System with ranibizumab (PDS) for the treatment of neovascular age-related macular degeneration (nAMD).Multicente...

Serum essential trace elements and toxic metals in Chinese diabetic retinopathy patients.

Nov 23, 2020

Trace elements are essential for the proper functioning of proteins, enzymes, and transcriptional factors. However, toxic metals will compete with essential trace elements, and damage enzymatic activi...

The SUSTech-SYSU dataset for automated exudate detection and diabetic retinopathy grading.

Nov 23, 2020

Automated detection of exudates from fundus images plays an important role in diabetic retinopathy (DR) screening and evaluation, for which supervised or semi-supervised learning methods are typically...

Prevalence and associated factors of glaucoma in the Russian Ural Eye and Medical Study.

Nov 23, 2020

To assess the prevalence and associated factors of glaucoma in a Russian population. The population-based Ural Eye and Medical Study included 5899 (mean age 59.0 ± 10.7 years; range 40-94 years...

Treat-and-extend versus fixed bimonthly treatment regimens for treatment-naive neovascular age-related macular degeneration: real world data from the Fight Retinal Blindness registry.

Nov 23, 2020

To compare the outcomes of two different antivascular endothelial growth factor treatment regimens for treatment-naive eyes with neovascular age-related macular degeneration in routine clinical care a...

Organoids and organ chips in ophthalmology.

Nov 23, 2020

Recent advances have driven the development of stem cell-derived, self-organizing, three-dimensional miniature organs, termed organoids, which mimic different eye tissues including the retina, cornea,...

What are Ophthalmology Patients Asking Online? An Analysis of the Eye Triage Subreddit.

Nov 20, 2020

Ophthalmology patients are seeking medical advice on social media websites like Reddit, where users are able to post comments and discuss issues pertaining to different topics that are organized in 's...

What can anisometropia tell us about eye growth?

Nov 20, 2020

The study explored the interocular differences in biometry to determine the potential role of other factors in refractive development. In 362 subjects Childhood Errors of Refraction study were studie...

Rapid assessment of avoidable blindness-based healthcare costs of diabetic retinopathy in Hungary and its projection for the year 2045

Nov 20, 2020

The purpose of this study was to estimate the total healthcare cost associated with DR in the population aged 18 years and older in Hungary, and its projection for the year 2045. A cost model was dev...

Ultra-wide-field scanning laser ophthalmoscopy and optical coherence tomography in FEVR: findings and its diagnostic ability

Nov 20, 2020

The study was done to describe some novel vitreoretinal microstructural findings in patients with mild FEVR on UWF-SLO and UWF optical coherence tomography (UWF-OCT) and to evaluate their clinical sig...

Outcomes of gonioscopy-assisted transluminal trabeculotomy in pseudoexfoliative glaucoma: 24-month follow-up

Nov 20, 2020

The study was done to report on outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in eyes with PXG. 103 eyes from 84 patients with PXG were enrolled to undergo a 360-degree ab interno...

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