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Ophthalmology General

Improving statistical power of glaucoma clinical trials using an ensemble of cyclical generative adversarial networks.

Dec 03, 2020

Albeit spectral-domain OCT (SDOCT) is now in clinical use for glaucoma management, published clinical trials relied on time-domain OCT (TDOCT) which is characterized by low signal-to-noise ratio, lead...

The Utility of Routine Fundus Photography Screening for Posterior Segment Disease: A Stepped-wedge, Cluster-randomized Trial in South India.

Dec 03, 2020

To assess whether routine fundus photography (RFP) to screen for posterior segment disease at community eye clinics in South India increases referral to the urban hospital for ophthalmology care.Stepp...

Efficacy and safety evaluation of benzalkonium chloride preserved eye-drops compared with alternatively preserved and preservative-free eye-drops in the treatment of glaucoma: a systematic review and meta-analysis

Dec 02, 2020

This study is a systematic review that compared the efficacy and safety of BAK-preserved eye-drops with AP and PF eye-drops. 3 online databases were searched for randomized controlled trials. Studies...

Anterior chamber particles are associated with a reduction of intraocular pressure after selective laser trabeculoplasty

Dec 02, 2020

This study was done to examine the correlation between IOP reduction and the number of hyper-reflective particles appearing in the anterior chamber following SLT. It was a prospective interventional ...

Selective laser trabeculoplasty versus medication for open-angle glaucoma: systematic review and meta-analysis of randomized clinical trials

Dec 02, 2020

Effective treatment for OAG is to reduce the IOP, with medical therapy being the typical first-line therapy. Alternative therapy is SLT, which is safe as it is effective in lowering the IOP. Whether S...

ORCA study: real-world versus reading centre assessment of disease activity of neovascular age-related macular degeneration (nAMD)

Dec 02, 2020

The prospective, non-interventional ORCA module of the OCEAN study was done with the purpose to evaluate the quality of SD-OCT image interpretation and treatment decisions by clinicians in German. The...

Comparison of various surgical techniques for optic disc pit maculopathy: vitrectomy with the internal limiting membrane (ILM) peeling alone versus inverted ILM flap ‘plug’ versus autologous scleral ‘plug’

Dec 02, 2020

This study was done with the purpose to compare the anatomical and visual outcomes of vitrectomy with the ILM peeling alone versus inverted ILM flap to plug the pit versus autologous scleral plug for ...

Comparison of OCT angiography in children with a history of intravitreal injection of ranibizumab versus laser photocoagulation for retinopathy of prematurity

Dec 02, 2020

To compare the foveal microvascular structure characteristics in children with a history of IVR versus LP for retinopathy of prematurity by OCTA. This was a cross-sectional study. A total of 17 child...

Long-term (20-year) real-world outcomes of intravenous chemotherapy (chemo reduction) for retinoblastoma in 964 eyes of 554 patients at a single center

Dec 02, 2020

IVC remains an important global salvage therapy for retinoblastoma. This study was done with the purpose to do an evaluation of long-term globe salvage at 5, 10, 15, and 20 years following frontline I...

Effect of low-dose atropine on myopia progression, pupil diameter, and accommodative amplitude: low-dose atropine and myopia progression

Dec 02, 2020

The study was done with the purpose to evaluate the effects of 0.01% and 0.02% atropine eye drops on myopia progression, pupil diameter, and accommodative amplitude in myopic children. It was a cohor...

Comparison of central visual sensitivity between monocular and binocular testing in advanced glaucoma patients using IMO perimetry

Dec 02, 2020

This study was conducted with the purpose to compare central visual sensitivity under monocular and binocular conditions in patients with glaucoma using the new IMO static perimeter. It was a cross-s...

First-in-human continuous 24-hour measurement of intraocular pressure and ocular pulsation using a novel contact lens sensor

Dec 02, 2020

This study was done with the purpose to assess the feasibility of a novel contact lens device for intraocular pressure and ocular pulse amplitude continuous measurements over 24 hours. This was a pro...

Effect of partial posterior vitreous detachment on spectral-domain optical coherence tomography retinal nerve fiber layer thickness measurements

Dec 02, 2020

The study was done to assess the effect of partial posterior vitreous detachment (pPVD) on spectral-domain OCT peripapillary retinal nerve fiber layer thickness (RNFL) measurements. Spectral-domain O...

Imaging Methods for Differentiating Pediatric Papilledema from Pseudopapilledema

Nov 30, 2020

Papilledema is an urgent ophthalmologic finding, as it indicates increased intracranial pressure, which may be caused by serious neurologic conditions like a brain tumor or meningitis. However, in chi...

Optical coherence tomography angiography in glaucoma: analysis of the vessel density-visual field sensitivity relationship.

Nov 30, 2020

Glaucoma, a well-defined group of progressive optic neuropathies is one of the leading causes of irreversible blindness worldwide. In order to stop or slow down the progression of glaucomatous vision ...

Prevalence, care-seeking practices and impact of self-reported vision impairment in Southwest Cameroon: a community-based study.

Nov 30, 2020

To establish the prevalence of self-reported vision impairment (VI) in Southwest Cameroon and describe associated care-seeking practices, functional limitations and economic hardships.A three-stage cl...

A novel c.980C>G variant in results in identifiable gyrate atrophy phenotype associated with retinal detachment in a young female.

Nov 30, 2020

: Gyrate atrophy of the choroid and retina (GA) is a rare autosomal recessive disorder characterized by nyctalopia, myopia, sharply demarcated expanding peripheral chorioretinal atrophic lesions, earl...

Characteristics of corneal high-order aberrations in adolescents with mild to moderate myopia.

Nov 30, 2020

This study investigated the characteristics of corneal higher-order aberrations (HOAs) of the anterior surface, posterior surface, and total cornea in adolescents with mild to moderate myopia.A total ...

The Impact of Image Registration for Ablation Orientation on Clinical Outcomes After Wavefront-Optimized Refractive Surgery in Eyes with Myopia and Astigmatism.

Nov 30, 2020

To compare the clinical outcomes from laser refractive surgery performed with the same laser with and without incorporating iris registration technology to compensate for ocular cyclotorsion.Single-si...

Relationship between eyelid margin irregularity and meibomian gland dropout.

Nov 30, 2020

To examine the relationship between lid margin abnormalities and meibomian gland loss in infrared meibography.This study was a retrospective chart review of 170 patients with dry eye disease. A correl...

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