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Ophthalmology General

Extending the Scope of Conceptual Density Functional Theory with Second Order Analytical Methodologies.

Feb 05, 2024

In the context of the growing impact of conceptual density functional theory (DFT) as one of the most successful chemical reactivity theories, response functions up to second order have now been widel...

Characterizing the Robustness of Distinct Clinical Assessments in Identifying Dry Eye Condition of Animal Models.

Feb 05, 2024

The study aims to characterize the robustness of distinct clinical assessments in identifying the underlying conditions of dry eye disease (DED), with a specific emphasis on the involvement of conjunc...

Association between systemic medication use and severity of dry eye signs and symptoms in the DRy eye assessment and management (DREAM) study.

Feb 05, 2024

Some systemic medications are reported to be associated with dry eye disease (DED), yet their associations with the severity of DED signs and symptoms are not well studied. To evaluate these associati...

Present and future screening programs for diabetic retinopathy: a narrative review.

Feb 05, 2024

Diabetes is a prevalent global concern, with an estimated 12% of the global adult population affected by 2045. Diabetic retinopathy (DR), a sight-threatening complication, has spurred diverse screenin...

Deciphering Immune-Related Gene Signatures in Diabetic Retinopathy: Insights from In Silico Analysis and In vitro Experiment.

Feb 05, 2024

Diabetes retinopathy (DR) is one of the most common microvascular consequences of diabetes, and the economic burden is increasing. Our aim is to decipher the relevant mechanisms of immune-related gene...

Fabrication of carboxymethyl cellulose-based thermo-sensitive hydrogels and inhibition of corneal neovascularization.

Feb 05, 2024

Corneal neovascularization (CNV) is a common multifactorial sequela of anterior corneal segment inflammation, which could lead to visual impairment and even blindness. The main treatments available ar...

Validation of WINROP algorithm as screening tool of retinopathy of prematurity among Egyptian preterm neonates.

Feb 05, 2024

Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness worldwide. Proper screening for ROP can prevent loss of vision. WINROP (weight, insulin-like growth factor 1, neo...

Amblyopia Care Trends Following Widespread Photoscreener Adoption.

Feb 05, 2024

Amblyopia can result in permanent vision loss if not properly treated before age 7 years. In 2017, the US Preventive Services Task Force recommended that vision screening should occur at least once in...

The incidence, clinical features, and management of essential infantile esotropia in the United Kingdom. A British Ophthalmology Surveillance Unit (BOSU) study.

Feb 05, 2024

A national study was undertaken through the British ophthalmology surveillance unit (BOSU) to determine the incidence, presenting features and management of essential infantile esotropia (EIE) in the ...

Sterile granulomatous panuveitis in dogs in the United Kingdom: A review of 33 cases.

Jan 29, 2024

To describe the clinical and histopathological features of a sterile granulomatous panuveitis syndrome in 33 dogs that underwent enucleation and ocular histopathology.Retrospective review of the medic...

Nutraceutical potential of olive pomace: insights from cell-based and clinical studies.

Jan 29, 2024

Olive oil production yields a substantial volume of by-products, constituting up to 80% of the processed fruits. The olive pomace by-product represents a residue of significant interest due to the div...

Adversarial learning-based domain adaptation algorithm for intracranial artery stenosis detection on multi-source datasets.

Jan 29, 2024

Intracranial arterial stenosis (ICAS) is characterized by the pathological narrowing or occlusion of the inner lumen of intracranial blood vessels. However, the retina can indirectly react to cerebrov...

Lipid Mediators in Glaucoma: Unraveling Their Diverse Roles and Untapped Therapeutic Potential.

Jan 29, 2024

Glaucoma is a complex neurodegenerative disease characterized by optic nerve damage and visual field loss and remains a leading cause of irreversible blindness. Elevated intraocular pressure (IOP) is ...

Managing the apparently blind child presenting in the first year of life: A review.

Jan 22, 2024

Severe vision impairment and blindness in childhood have a significant health burden on the child, family and society. This review article seeks to provide a structured framework for managing the appa...

A multi-cohort genome-wide association study in African ancestry individuals reveals risk loci for primary open-angle glaucoma.

Jan 22, 2024

Primary open-angle glaucoma (POAG), the leading cause of irreversible blindness worldwide, disproportionately affects individuals of African ancestry. We conducted a genome-wide association study (GWA...

Open Fundus Photograph Dataset with Pathologic Myopia Recognition and Anatomical Structure Annotation.

Jan 22, 2024

Pathologic myopia (PM) is a common blinding retinal degeneration suffered by highly myopic population. Early screening of this condition can reduce the damage caused by the associated fundus lesions a...

Relationship between dynamic visual acuity and static visual acuity, refractive error, and binocular vision in elite soccer players.

Jan 22, 2024

In many sports, dynamic visual acuity is used. In order to improve dynamic visual acuity, it is important to understand the aspects of the visual system that can cause compromise.To investigate the pa...

ER-1 deficiency induces inflammation and lipid deposition in meibomian gland and lacrimal gland.

Jan 22, 2024

To investigated the role of estrogen receptor-1 (ER-1) in maintaining homeostasis in ocular surface.ER-1-knockout (ER-1KO) mice were studied at 4 months of age. The ocular surface was examined using a...

Social Determinants of Dry Eye in the United States: A Systematic Review.

Jan 22, 2024

Goal To conduct a systematic review to summarize current evidence on associations between social determinants of health (SDOH) indicators and dry eye in the U.S. Systematic review We followed...

Salidroside protects RGC from pyroptosis in diabetes-induced retinopathy associated with NLRP3, NFEZL2 and NGKB1, revealed by network pharmacology analysis and experimental validation.

Jan 22, 2024

To investigate the effect of salidroside (SAL) in protecting retinal ganglion cell (RGC) from pyroptosis and explore associated molecular network mechanism in diabetic retinapathy (DR) rats.HE, Nissl ...

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