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Ophthalmology General

TNF is a critical cytokine in age-related dry eye disease.

Aug 28, 2023

Aging is a complex biological process that is characterized by low-grade inflammation, called inflammaging. Aging affects multiple organs including eye and lacrimal gland. Tumor necrosis factor (TNF) ...

Limbal Stem Cell Dysfunction Induced by Severe Dry Eye via Activation of the p38 MAPK Signaling Pathway.

Aug 28, 2023

Severe dry eye (SDE) can cause grievous damage of the ocular surface and result in vision impairment and even blindness. To investigate the fate of limbal stem cells in SDE and the underlying mechanis...

The effect of Central and peripheral thyroid resistance indices on diabetic retinopathy: a study of hospitalized euthyroid patients with T2DM in China.

Aug 28, 2023

This study aims to explore the correlation between central and peripheral thyroid resistance indices and diabetic retinopathy(DR) in patients with type 2 diabetes mellitus (T2DM), so as to provide a c...

Genome-wide meta-analysis identifies novel loci and improves disease prediction of age-related macular degeneration.

Aug 28, 2023

To identify novel Age-related macular degeneration (AMD) loci and establish polygenic prediction model DESIGN: Genome-wide association study (GWAS) and polygenic risk score (PRS).Total of 64,885 Europ...

The Novel Optical Design and Clinical Classification of a Wavefront-Shaping Presbyopia-Correcting Intraocular Lens.

Aug 28, 2023

To evaluate the clinical rationale of wavefront-shaping technology, describe how intraocular lenses (IOLs) using wavefront-shaping technology are differentiated from refractive or diffractive optical ...

Modelling morbidity for neglected tropical diseases: the long and winding road from cumulative exposure to long-term pathology.

Aug 21, 2023

Reducing the morbidities caused by neglected tropical diseases (NTDs) is a central aim of ongoing disease control programmes. The broad spectrum of pathogens under the umbrella of NTDs lead to a range...

Attitudes and knowledge of myopia management by Spanish optometrists.

Aug 21, 2023

To investigate the knowledge, training and clinical practice of Spanish optometrists about preventing and controlling myopia progression.A web-based questionnaire was distributed to Spanish optometris...

A large-scale analysis of refractive errors in students attending public primary schools in Mexico.

Aug 21, 2023

A cross-sectional, retrospective study was conducted from September 2013 through July 2014 to determine the prevalence of refractive errors among students attending public primary schools in Mexico. A...

Tear film changes in symptomatic versus asymptomatic video display terminal users following computer challenge test.

Aug 21, 2023

To assess the real-time changes in the tear film and ocular surface of symptomatic video display terminal (VDT) versus asymptomatic users.A total of 35 symptomatic (29 ± 5.6 years; Group 1, mild ...

Ocular Pharmacokinetics and Toxicity of Nanoparticular Acetazolamide: in vivo Distribution and safety of PHBV-ACZ Nanoparticle.

Aug 21, 2023

Diabetic macular edema (DME) is defined as fluid accumulation in the macular region, between the retinal layers, due to many diseases, especially diabetes. DME is one of the major complications of dia...

Loss of social independence in patients with neurofibromatosis type 2: a follow-up study using a national registry in Japan.

Aug 21, 2023

For patients with neurofibromatosis type 2 (NF2), maintaining an independent state of living is important. The present study aimed to examine the loss of social independence (i.e., a status that patie...

ETMT: A Tool for Eye-Tracking-Based Trail-Making Test to Detect Cognitive Impairment.

Aug 14, 2023

The growing number of people with cognitive impairment will significantly increase healthcare demand. Screening tools are crucial for detecting cognitive impairment due to a shortage of mental health ...

Transitions in vascular ultrasonography findings of temporal arteritis in a GCA case with progressive temporal headache and visual impairment.

Aug 14, 2023

The European League Against Rheumatism and the American College of Rheumatology have stated that the halo sign on vascular ultrasonography (v-US) is relevant in diagnosing giant cell arteritis (GCA) a...

Prevalence of Accommodative Microfluctuations in Eyes after Cataract Surgery.

Aug 14, 2023

We aimed to evaluate the existence of accommodative microfluctuations in eyes after cataract surgery.This retrospective observational cohort study included 1160 eyes of 713 patients (mean age: 72.5 ±...

Comparison of visual performance and image quality between a myopia-control contact lens and a single-vision contact lens.

Aug 14, 2023

This study aimed to evaluate the visual performance and image quality of concentric dual-focus-designed contact lenses (CLs) compared with single-vision CLs in myopic Chinese people.Twenty myopic volu...

The Impact of Pregnancy on Diabetic Retinopathy: a Single-Center Study of Clinical Risk Factors.

Aug 14, 2023

This study aimed to provide information on modifiable and non-modifiable risk factors for the progression and development of diabetic retinopathy (DR) and diabetic macular edema (DME). This retrospect...

Relationship of Choroidal Microvasculature Dropout and Beta-Zone Parapapillary Area with Visual Field Changes in Glaucoma.

Aug 14, 2023

To evaluate the association between rates of choroidal microvasculature dropout (MvD) change, beta-zone parapapillary atrophy (β-PPA) area change, and visual field (VF) changes in primary open-angle ...

The Royal College of Ophthalmologists' National Ophthalmology Database study of cataract surgery: report 16, influence of remuneration model on choice of intraocular lens in the UK.

Aug 14, 2023

Cataract surgery with intraocular lens (IOL) implantation is one of the most commonly performed surgeries worldwide. Within the UK, publicly funded cataract surgery is remunerated by two models: (1) "...

Six Year Incidence and Risk Factors for Primary Open Angle Glaucoma and Ocular Hypertension: The Singapore Epidemiology of Eye Diseases Study.

Aug 14, 2023

To determine the incidence and risk factors for primary open angle glaucoma (POAG) and ocular hypertension (OHT) in a multi-ethnic Asian population.Population based, cohort study PARTICIPANTS: The Sin...

Comparison of Myopia Progression among Myopic Children with Intermittent Exotropia and No Strabismus.

Aug 07, 2023

Myopia is a highly prevalent condition in the pediatric population that is commonly comorbid with intermittent exotropia. Our study found a trend towards significance in the reduction of myopia progre...

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