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Ophthalmology General

Aniridia and the ocular surface: Medical and surgical problems and solutions.

Nov 29, 2021

Congenital aniridia is a multisystemic genetic disease due to a mutation in PAX6 gene which severely affects the development and functionality of the human eyes. In patients affected by the mutation, ...

Barriers and enablers to diabetic eye screening attendance: an interview study with young adults with type 1 diabetes.

Nov 29, 2021

To identify barriers and enablers of diabetic eye screening (DES) attendance amongst young adults with diabetes living in the UK.Semi-structured qualitative interviews with adults aged 18-34 years wit...

Protective role of melatonin in breast cancer: what we can learn from women with blindness.

Nov 29, 2021

This review proposes an overall vision of the protective and therapeutic role of melatonin in breast cancer: from the specific cases of blind women and their reduction of breast cancer incidence to al...

Corneal Endothelial Cell Loss After PRESERFLO™ MicroShunt Implantation in the Anterior Chamber: Anterior Segment OCT Tube Location as a Risk Factor.

Nov 29, 2021

To analyze the effects of PRESERFLO on corneal endothelial cell density (ECD).Forty-six eyes that underwent PRESERFLO implantation were followed up for 12 months. Specular microscopy was performed pr...

Minimizing iridium oxide electrodes for high visual acuity subretinal stimulation.

Nov 22, 2021

Vision loss from diseases of the outer retina, such as Age-Related Macular Degeneration (AMD), are among the leading causes of irreversible blindness in the world today. The goal of retinal prosthetic...

Extrinsic and Intrinsic Factors Regulating Juvenile Refractive Development and Eye Growth.

Nov 22, 2021

Peripheral refraction and accommodation are intrinsic factors that were once hypothesized to trigger myopia but are now controversial. Previously, home nearwork environment (i.e., extrinsic factor) wa...

Corneal power measurements by ray tracing in eyes after small incision lenticule extraction for myopia with a combined Scheimpflug Camera-Placido disk topographer.

Nov 22, 2021

To evaluate the accuracy of the measurements of corneal power obtained by ray tracing with a combined Scheimpflug camera-Placido disk corneal topographer (Sirius) in eyes after small incision lenticul...

Tear Film Surface Quality in Modern Daily Disposable Contact Lens Wear.

Nov 22, 2021

As reported previously, tear film surface quality (TFSQ) should be considered in contact lens (CL) fitting. This study followed noninvasive keratograph tear film break-up time (NIKBUT) in CL wearers f...

Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model.

Nov 22, 2021

We have demonstrated that deletion of fibroblast growth factor receptor 2 gene (Fgfr2) leads to Meibomian gland (MG) atrophy in an inducible conditional knockout mouse model, referred as Fgfr2. Herein...

Bulk Gene Expression Deconvolution Reveals Infiltration of M2 Macrophages in Retinal Neovascularization.

Nov 22, 2021

This study interrogated the transcriptional features and immune cellular landscape of the retinae of rats subjected to oxygen-induced retinopathy (OIR).Bulk RNA sequencing was performed with retinal R...

Glyceraldehyde-3-phosphate dehydrogenase and glutamine synthetase inhibition in the presence of pro-inflammatory cytokines contribute to the metabolic imbalance of diabetic retinopathy.

Nov 22, 2021

Diabetic retinopathy (DR) is the leading cause of vision impairment in working age adults. In addition to hyperglycemia, retinal inflammation is an important driving factor for DR development. Althoug...

A Comparison Among Microperimetry, Standard Automated Perimetry and Spectral Domain Optical Coherence Tomography in the Evaluation of the Macula in Glaucoma Eyes with Hemifield Defects.

Nov 22, 2021

To evaluate the correlation between macular integrity assessment (MAIA) and standard automated perimetry (SAP) in detecting macular function damage in glaucoma and to explore the relationship between ...

Chronic social defeat stress causes retinal vascular dysfunction.

Nov 22, 2021

The roles of vascular dysfunction and chronic stress have been extensively discussed in the pathophysiology of glaucoma. Our aim was to test whether chronic stress causes retinal vascular dysfunction ...

«Do Not Do» recommendations for retinopathies: A mixed consensus study.

Nov 15, 2021

Among the main causes of blindness and severe vision loss are age-related macular degeneration, diabetic macular oedema, and retinal vein occlusion. The «Do Not Do» recommendations are strategies to...

Accuracy of Newer Generation IOL Power Calculation Formulas in Eyes With High Axial Myopia.

Nov 15, 2021

To compare the accuracy of the Barrett Universal II, Emmetropia Verifying Optical (EVO), Haigis, Kane, and SRK/T formulas for intraocular lens power calculation in patients with high axial myopia.In t...

Changes in refractive status of amblyopic patients with partially refractive esotropia.

Nov 15, 2021

To investigate the changes in refractive status of amblyopic patients with partially refractive esotropia (PAET).Amblyopic patients with PAET were enrolled. Non-amblyopic patients with full refractive...

Update on Pain Management After Advanced Surface Ablation.

Nov 15, 2021

To provide an update for postoperative pain control strategies to help ophthalmic surgeons establish a more effective management plan for patients who underwent advanced surface ablation surgeries.Goo...

Tear osmolarity, dry eye syndrome, blepharospasm and botulinum neurotoxin.

Nov 15, 2021

To assess the severity of dry eye disease in patients with blepharospasm (BEB) before (control) and after injection of botulinum neurotoxin A (BoNT/A).Cross-sectional study.Patients with clinically di...

Normative Data of Ocular Biometry, Optical Coherence Tomography, and Electrophysiology Conducted for Cynomolgus Macaque Monkeys.

Nov 15, 2021

To present normative data of optical coherence tomography (OCT) parameters, electrophysiological tests, and optical biometry conducted for cynomolgus monkeys.Multimodal examinations were performed for...

An Open-Source Deep Learning Network for Reconstruction of High-Resolution OCT Angiograms of Retinal Intermediate and Deep Capillary Plexuses.

Nov 15, 2021

We propose a deep learning-based image reconstruction algorithm to produce high-resolution optical coherence tomographic angiograms (OCTA) of the intermediate capillary plexus (ICP) and deep capillary...

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