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Ophthalmology General

Senescence marker protein 30 (SMP30) protects against high glucose-induced apoptosis, oxidative stress and inflammatory response in retinal ganglion cells by enhancing Nrf2 activation via regulation of Akt/GSK-3β pathway.

Oct 25, 2021

Senescence marker protein 30 (SMP30) is an aging-related protein that participates in the regulation of tissue damage under various pathological conditions. However, the role of SMP30 in mediating hig...

Effect of papaverine on axonal outgrowth of primary retinal ganglion cells of Sprague Dawley rats.

Oct 25, 2021

Increasing the level of cyclic adenosine 3, 5'-monophosphate is an important mechanism for axon outgrowth and recovery of central nervous system function. This study aimed to investigate the effects o...

Patient Expectation, Satisfaction and Clinical Outcomes with a New Multifocal Intraocular Lens.

Oct 25, 2021

To report patient expectations, visual performance and satisfaction with AcrySof IQ PanOptix multifocal intraocular lens in a heterogeneous patient group. Additionally, determine if identifiable pre-o...

Optical biometry and influence of media opacity due to cataract on development of axial length in NorthEast Indian paediatric patients- A prospective study.

Oct 25, 2021

To study the influence of media opacity due to cataract on the development of axial length in paediatric patients from North-East India, using optical biometry.This is a prospective, observational stu...

The influence of early visual deprivation on audio-spatial working memory.

Oct 18, 2021

This study investigates how spatial working memory skills, and the processing and retrieval of distal auditory spatial information are influenced by visual experience.We developed an experimental para...

Focused ultrasound stimulation on meibomian glands for the treatment of evaporative dry eye.

Oct 18, 2021

Current treatments for meibomian gland dysfunction have several limitations, creating a necessity for other advanced treatment options. The purpose of this study is to determine the effectiveness of f...

An overview of current alternative models in the context of ocular surface toxicity.

Oct 18, 2021

The 21st century has seen a steadily increasing social awareness of animal suffering, with increased attention to ethical considerations. Developing new integrated approaches to testing and assessment...

Joint Learning of Multi-level Tasks for Diabetic Retinopathy Grading on Low-resolution Fundus Images.

Oct 18, 2021

Diabetic retinopathy (DR) is a leading cause of permanent blindness among the working-age people. Automatic DR grading can help ophthalmologists make timely treatment for patients. However, the existi...

Degree of Myopia and Glaucoma Risk: A Dose-Response Meta-Analysis.

Oct 18, 2021

To verify the dose-response relation between degree of myopia and open-angle glaucoma (OAG) risk DESIGN: Dose-response meta-analysis METHODS: We searched the PubMed, EMBASE, and Cochrane databases for...

Anterior Chamber Laser Flare Photometry After Diode Laser Cyclophotocoagulation.

Oct 18, 2021

The aim of this study was to evaluate changes in intraocular inflammation according to energy delivered per eye during transscleral diode laser cyclophotocoagulation (TDLC) in refractory glaucoma usin...

Blindness in glaucoma: primary open-angle glaucoma versus primary angle-closure glaucoma-a meta-analysis.

Oct 18, 2021

To estimate the risk of blindness with primary angle-closure glaucoma (PACG) compared to primary open-angle glaucoma (POAG) in those population-based studies that reported blindness rates for both PAC...

X-linked Retinoschisis: Novel Clinical Observations and Genetic Spectrum in 340 Patients.

Oct 11, 2021

To describe the natural course, phenotype and genotype of patients with X-linked retinoschisis (XLRS).Retrospective cohort study.Three hundred forty patients with XLRS from 178 presumably unrelated fa...

Single-vision spectacle use and myopia progression in children with low myopia, a propensity score matching study.

Oct 11, 2021

To investigate the impact of single-vision spectacle use on myopia progression in children with low myopia.MYOSOTIS is a prospective myopia screening survey including all 46 primary and junior high sc...

Comparison of subconjunctival microinvasive glaucoma surgery and trabeculectomy.

Oct 11, 2021

To assess surgical success and the post-operative development of intraocular pressure between XEN45 gelstent, Preserflo MicroShunt and trabeculectomy with mitomycin C.Data from 105 eyes from 105 patie...

Efficacy of the Systane iLux Thermal Pulsation System for the Treatment of Meibomian Gland Dysfunction After 1 Week and 1 Month: A Prospective Study.

Oct 11, 2021

To assess 1-week and 1-month efficacy of Systane iLux thermal pulsation treatment for meibomian gland dysfunction (MGD).This prospective, nonrandomized, open-label, multicenter study enrolled 30 adult...

Electrostatic and Covalent Assemblies of Anionic Hydrogel-Coated Gold Nanoshells for Detection of Dry Eye Biomarkers in Human Tears.

Oct 11, 2021

Although dry eye is highly prevalent, many challenges exist in diagnosing the symptom and related diseases. For this reason, anionic hydrogel-coated gold nanoshells (AuNSs) were used in the developmen...

Lycium barbarum polysaccharides attenuates high glucose-induced diabetic retinal angiogenesis by rescuing the expression of miR-15a-5p in RF/6A cells.

Oct 11, 2021

Lycium barbarum L., a classical traditional Chinese Medicine, has long been used to treat ocular diseases. Lycium barbarum polysaccharides (LBP) is an effective component of Lycium barbarum L. with a ...

Racial and socioeconomic differences in eye care utilization among Medicare beneficiaries with glaucoma.

Oct 11, 2021

Evaluate differences in eyecare utilization among glaucoma patients by race and socioeconomic status (SES).Retrospective cohort study.Representative 5% sample of Medicare beneficiaries >65 years wi...

Soft substrate stiffness modifies corneal epithelial stem cell phenotype through hippo-YAP/notch pathway crosstalk.

Oct 11, 2021

Corneal disease remains to be one of the leading causes of blindness in the world and limbal stem cell (LSC) therapy is a promising therapy for LSC deficiency, which is associated with the diseased co...

Health Care Price Transparency in Ophthalmology.

Oct 11, 2021

Health care price transparency legislation is intended to reduce the ambiguity of hospital charges and the resultant financial stress faced by patients.To evaluate the availability, usability, and var...

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