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Critical Care General

Are Patients With a History of Septic Arthritis Undergoing Total Knee Arthroplasty at Higher Risk for Revision Surgery? A Single-Center Study.

Apr 06, 2020

The decision to perform a total knee arthroplasty (TKA) on a previously infected knee is made complicated by the higher risk for both a periprosthetic joint infection (PJI) and early failure. There is...

Isolated septic facet joints: an underdiagnosed distinct clinical entity.

Apr 06, 2020

We review a series of isolated septic facet joints (ISFJ) that present as a distinct clinical entity compared with spondylodiscitis. We aim to raise awareness that septic facet joints are not a rare e...

Serious Infections in People with Gout in the United States: A National Study of Incidence, Time-trends and Outcomes.

Apr 06, 2020

To study the epidemiology of hospitalized serious infections in people with gout.We identified people with gout hospitalized with a primary diagnosis of pneumonia, sepsis/bacteremia, urinary tract inf...

[Analysis of the frequency of polytraumatized patients in motorcycle accidents in the pediatric publication attended in the Pediatric Hospital of Sinaloa between the years 2015 and 2017].

Apr 06, 2020

Determine the frequency of polytraumatized pediatric patients involved in motorcycle accidents treated at the Pediatric Hospital of Sinaloa between 2015 and 2017, as well as to determine the frequency...

DPP-4 inhibitor reduces striatal microglial deramification after sensorimotor cortex injury induced by external force impact.

Apr 06, 2020

Dipeptidyl peptidase-4 inhibitors (or gliptins), a class of antidiabetic drugs, have recently been shown to have protective actions in the central nervous system. Their cellular and molecular mechanis...

Assessment of Panfacial Fractures in the Pediatric Population.

Apr 06, 2020

Management of panfacial fractures is critical and often difficult in adults; however, there is little to no literature regarding these fractures in the pediatric population. In this study, we present ...

Alternative substrate metabolism depends on cerebral metabolic state following traumatic brain injury.

Apr 06, 2020

Decreases in energy metabolism following traumatic brain injury (TBI) are attributed to impairment of glycolytic flux and oxidative phosphorylation. Glucose utilization post-TBI is decreased while adm...

The potential of head acceleration measurement to augment current best practice in concussion screening in professional Australian football players.

Apr 06, 2020

To explore the potential utility of head acceleration event (HAE) measurements to augment identification of players for further concussion screening in non-helmeted contact sport.Prospective observati...

Role of dipstick proteinuria for predicting cardiovascular events: a Japanese cardiovascular hospital database analysis.

Apr 06, 2020

Initial screening for proteinuria by urine dipstick test (UDT) may be useful for predicting clinical outcomes. The Shinken Database includes all the new patients visiting the Cardiovascular Institute ...

The prognostic impact of the controlling nutritional status (CONUT) score in patients undergoing cardiovascular surgery.

Apr 06, 2020

Various postoperative predictive markers following cardiovascular surgery have been examined for use in the current aging population. The controlling nutritional status (CONUT) score, which is advocat...

The Association of ICU Acuity with Adherence to ICU Evidence-Based Processes of Care.

Apr 06, 2020

Admission to high-acuity intensive care units (ICUs) has been associated with improved outcomes compared to low-acuity ICUs, although the mechanism for these findings is unclear.Do high-acuity ICUs mo...

Mid-term results after simultaneous carotid artery stenting and cardiac surgery.

Apr 06, 2020

The presence of carotid artery disease is known risk factor for perioperative stroke in cardiac surgery. The optimal management of patients with concomitant heart and carotid artery disease is not kno...

Efficacy of continuous positive airway pressure (CPAP) in the prevention of cardiovascular events in patients with obstructive sleep apnea: Systematic review and meta-analysis.

Apr 06, 2020

Obstructive sleep apnea (OSA) commonly occurs in patients with increased cardiovascular (CV) risk, and continuous positive airway pressure (CPAP) is the preferred therapy for these patients. The aim o...

The Design of and Rationale for the Effect of Perioperative Inhaled Tiotropium for Patients with Chronic Obstructive Pulmonary Disease in Esophageal Cancer Surgery (EPITOPE): an Open-Label, Randomized, Parallel-Group Study.

Apr 06, 2020

Pneumonia is one of the most frequently occurring complications after esophagectomy and is associated with increased operative mortality. Chronic obstructive pulmonary disease (COPD) is known to be a ...

Beyond heart failure and ischemic heart disease: a scoping review of novel uses of ivabradine in adults.

Apr 06, 2020

Ivabradine lowers heart rate by inhibiting the hyperpolarization-activated current in pacemaker cells, and its use for the treatment of heart failure (HF) and ischemic heart disease (IHD) is well desc...

Mortality rate of COVID-19 patients on ventilators

Mar 30, 2020

Written by Physician's Weekly Blogger, Skeptical Scalpel Although at the time I wrote this over 33,000 people had died from COVID 19 infections worldwide, the numbers of patients dying in intensive...

Intraoperative Neurophysiologic Monitoring Correlates with Neurologic Outcome After Endovascular and Surgical Treatment of a Cervical Arteriovenous Malformation.

Mar 30, 2020

 The treatment of spinal intramedullary arteriovenous malformations (AVMs) presents the risk of spinal cord ischemia because of the vascular nidus and their feeding arteries involving and supplying ...

The αC helix of TIRAP holds therapeutic potential in TLR-mediated autoimmune diseases.

Mar 30, 2020

Despite being crucial for combating microbes, paradoxical Toll-like receptors (TLRs) signaling have been associated with the aggravation of multiple immune disorders such as systemic lupus erythematos...

HDAC6 promotes sepsis development by impairing PHB1-mediated mitochondrial respiratory chain function.

Mar 30, 2020

This study was aimed at investigating the regulation of mitochondrial function by histone deacetylase 6 (HDAC6) and the role of HDAC6 in the development and progression of sepsis.HDAC6 downregulated P...

Down-regulation of lncRNA CASC9 aggravates sepsis-induced acute lung injury by regulating miR-195-5p/PDK4 axis.

Mar 30, 2020

Long non-coding RNA (lncRNA) cancer susceptibility candidate 9 (CASC9) is reported to be linked to cancers. This research aims to explore the role and possible mechanism of CASC9 in lung injury induce...

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