Conference Highlights: CROI 2020
New research was presented at CROI 2020, the annual Conference on Retroviruses and Opportunistic...
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HIV/AIDS
Osteoporosis, BMD & Fracture Risk in PLHIV
With significant improvements in the treatment of HIV in recent years, life expectancy in patients...
Read MoreHome-based HIV testing: Using different strategies among transgender women in Argentina.
In Argentina, HIV prevalence among transgender women (TGW) has been reported at 34%. The stigma is one of the most important factors limiting their access to healthcare services. The aims of this study were to compare different...
Read MoreSimulating system dynamics of the HIV care continuum to achieve treatment as prevention.
The continuing HIV pandemic calls for broad, multi-sectoral responses that foster community control of local prevention and care services, with the goal of leveraging high quality treatment as a means of reducing HIV incidence....
Read MoreInteractive molecular dynamics in virtual reality for accurate flexible protein-ligand docking.
Simulating drug binding and unbinding is a challenge, as the rugged energy landscapes that separate bound and unbound states require extensive sampling that consumes significant computational resources. Here, we describe the use...
Read MoreMid-trimester cervical length not associated with HIV status among pregnant women in Botswana.
HIV-infected women on antiretroviral therapy have a higher risk of preterm birth than HIV-uninfected women in Botswana. To better understand the mechanism for preterm birth among HIV-infected women, we evaluated whether...
Read MoreFatal overdose prevention and experience with naloxone: A cross-sectional study from a community-based cohort of people who inject drugs in Baltimore, Maryland.
Overdose is a leading cause of death in the United States, especially among people who inject drugs (PWID). Improving naloxone access and carrying among PWID may offset recent increases in overdose mortality associated with the...
Read MoreIdentification of gp120 polymorphisms in HIV-1 B subtype potentially associated with resistance to fostemsavir.
We evaluated natural resistance to the new antiretroviral fostemsavir and its potential association with other HIV-1 gp120 polymorphisms.A total of 1997 HIV-1 B subtype gp120 sequences from the Los Alamos HIV Database were...
Read MoreDevelopment and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV.
The widespread use of highly active antiretroviral treatments has dramatically changed the prognosis of people living with HIV (PLWH). However, such treatments have to be taken lifelong raising issues regarding the maintenance...
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