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HIV/AIDS

For Patients Taking PrEP, Poor Adherence Drives HIV Seroconversions

Oct 03, 2022

HIV seroconversions among patients prescribed PrEP were driven by poor adherence, with many patients who acquired HIV reporting low self-perceived risk for HIV. “PrEP is highly effective when...

Less than One-Quarter of PrEP Users Vaccinated Against HPV

Sep 27, 2022

Pre-exposure prophylaxis (PrEP) for HIV prevention has been shown to be an effective strategy and is indicated for people at increased risk for infection from sexual contact or injection drug use. “...

inDEPTH: HIV & Prostate Cancer Prevention

Sep 19, 2022

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HIV Positive Women and Postpartum Contraception

Sep 16, 2022

For a study, researchers sought to understand that contrary to those without HIV, women with HIV had a higher rate of unplanned pregnancies. To lower the rate of perinatal HIV transmission globally, t...

Prevention Strategies ‘Critical’ as Diabetes Rates Rise in Patients With HIV

Sep 15, 2022

As diabetes rates continue to rise in patients with HIV, research is needed to address the modifiable and HIV-related risk factors related to this increase. “Adults with HIV have a greater ri...

Patients with Genotypic NRTI Resistance Treated with Bictegravir/Emtricitabine/Tenofovir Alafenamide

Sep 13, 2022

There is no known resistance to the individual components of the HIV medication bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF). The effectiveness of B/F/TAF has been demonstrated in several...

D/C/F/TAF in Treatment-naïve (AMBER) & Virologically Suppressed (EMERALD)

Sep 13, 2022

The purpose of this study was to compare the efficacy and safety results for AMBER and EMERALD patients with and without baseline neurological and/or psychiatric comorbidities (NPCs). Both the AMBER a...

Compassionate Use of LA Cabotegravir Plus Rilpivirine for HIV-1 Patients

Sep 13, 2022

ViiV Healthcare and Janssen backed a single-patient request program where doctors could seek compassionate use of oral and long-acting (LA) cabotegravir + rilpivirine for persons living with HIV-1.  ...

Premature, Accentuated, and Accelerated Aging in HIV People

Sep 13, 2022

Human immunodeficiency virus (HIV's) effect on how one age is controversial and poorly understood. Researchers compared the occurrence of 4 age-related non-communicable diseases in those with and with...

Effect of HIV and ART Use on Body Weight Changes in a Cohort With & Without HIV

Sep 13, 2022

Obesity and the diseases caused by being overweight are common among those with the Human immunodeficiency virus (HIV). Researcher’s study's overarching objective was to identify and assess characte...

Blood-borne Virus (BBVs) Testing in Emergency Departments

Sep 13, 2022

Blood-borne viruses (BBVs) cause significant morbidity and mortality worldwide. For populations at high risk of BBVs but less inclined to seek out primary care, Emergency departments (EDs) provide an ...

Harms Vs Benefits of Opioid Prescription Changes in HIV

Jun 17, 2022

Providers should not continue prescribing opioids to patients with HIV when risks outweigh benefits, but they need to factor the risks of stopping opioids into the equation. “There are specif...

A Rare Case of Good Outcome of Hodgkin Lymphoma in a Patient with HIV on Antiretroviral Therapy (ART).

May 16, 2022

BACKGROUND Recent reports have shown an increased incidence of Hodgkin lymphoma (HL) in patients treated with antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection. This report...

Gender, migration and violence among third country nationals accessing the sexual health clinic in Malta.

May 16, 2022

In 2020 the number of displaced people worldwide reached 41.3 million (IOM, 2020). Among them, are many migrants and refugees at risk of sexual and gender-based violence (SGBV). Healthcare providers h...

Social & Structural Factors Impact PrEP Uptake Among Cisgender Women

May 12, 2022

A study published in AIDS and Behavior identified social and structural factors that impacted PrEP uptake, but also found that women facing barriers to PrEP still initiated it. “Nearly 20% of...

The European & Developing Countries Clinical Trials Partnership (EDCTP) Knowledge Hub: developing an open platform for facilitating high-quality clinical research.

May 09, 2022

There is stark global inequity in health research in terms of where studies happen, who leads the research and the ultimate beneficiaries of the results generated. Despite significant efforts made, li...

Frontal lobe microglia, neurodegenerative protein accumulation, and cognitive function in people with HIV.

May 09, 2022

Microglia are implicated in Alzheimer's Disease (AD) pathogenesis. In a middle-aged cohort enriched for neuroinflammation, we asked whether microgliosis was related to neocortical amyloid beta (A[Form...

Exposure of human immune cells, to the antiretrovirals efavirenz and lopinavir, leads to lower glucose uptake and altered bioenergetic cell profiles through interactions with SLC2A1.

Apr 25, 2022

SLC2A1 mediates glucose cellular uptake; key to appropriate immune function. Our previous work has shown efavirenz and lopinavir exposure inhibits T cell and macrophage responses, to known agonists, l...

Lifestyle factors associated with sex differences in Kaposi sarcoma incidence among adult black South Africans: A case-control study.

Apr 18, 2022

Kaposi Sarcoma (KS) is endemic in several countries in Southern and Eastern Africa, relatively rare worldwide but a leading cancer among people living with HIV. KS has always been more common in adult...

Acute Kidney Injury Among Patients With HIV

Apr 08, 2022

While antiretroviral therapy has changed the paradigm for patients with HIV, these individuals still experience an increased risk for comorbid conditions, including kidney disease. “Antiretro...