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Psychiatry General

Therapeutic effects of Silexan on somatic symptoms and physical health in patients with anxiety disorders: A meta-analysis.

Mar 01, 2021

A meta-analysis was performed to examine therapeutic effects of Silexan on somatic symptoms, including insomnia/fatigue, and physical health in patients with anxiety disorders. Five randomized, placeb...

Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder.

Mar 01, 2021

Identifying brain processes involved in the risk and development of mental disorders is a major aim. We recently reported substantial interindividual heterogeneity in brain structural aberrations amon...

The prevalence and features of schizophrenia among individuals with gambling disorder.

Mar 01, 2021

Few studies have analyzed the comorbid presence of gambling disorder (GD) with schizophrenia, its sociodemographic correlates and clinical implications. This study estimated the prevalence of the dual...

Cortical expression of the RAPGEF1 gene in schizophrenia: investigating regional differences and suicide.

Mar 01, 2021

Rap guanine nucleotide exchange factor 1 (RAPGEF1) is involved in cell adhesion and neuronal migration. Previously we found lower RAPGEF1 mRNA levels in Brodmann's area (BA) 9 in subjects with schizop...

Problematic internet use: The effect of comorbid psychopathology on treatment outcomes.

Mar 01, 2021

Problematic Internet use (PIU) behaviours involve one's maladaptive Internet use and have been often described as secondary manifestations of pre-existing psychopathology. Furthermore, different profi...

Hand therapists' perspectives and practices related to musculoskeletal pain: A biopsychosocial lens.

Mar 01, 2021

While the biopsychosocial model is advocated for pain management, biomedical approaches continue to dominate in practice. Understanding musculoskeletal clinicians' perspectives and practices related t...

Heart-focused breathing and perceptions of burden in Alzheimer's caregivers: An online randomized controlled pilot study.

Mar 01, 2021

Informal caregivers of patients with Alzheimer's disease (AD) often experience high stress and reduced wellbeing and quality of life. HeartMath's Heart Lock-In® technique has been shown to reduce str...

Heart-focused breathing and perceptions of burden in Alzheimer's caregivers: An online randomized controlled pilot study.

Mar 01, 2021

Informal caregivers of patients with Alzheimer's disease (AD) often experience high stress and reduced wellbeing and quality of life. HeartMath's Heart Lock-In® technique has been shown to reduce str...

Serum NFL levels predict progression of motor impairment and reduction in putamen dopamine transporter binding ratios in de novo Parkinson's disease: An 8-year longitudinal study.

Mar 01, 2021

Neurofilament light chain (NFL) level in biofluids is a sensitive measure of axonal damage and a promising biomarker in neurodegenerative diseases. In Parkinson's disease (PD), NFL can distinguish PD ...

Levodopa affects spike and local field synchronisation in the pedunculopontine nucleus of a rat model of Parkinson's disease.

Mar 01, 2021

The pedunculopontine nucleus (PPN) undergoes significant anatomic and electrophysiological alterations in Parkinson's disease (PD), severely impacting locomotion. However, the effect of 6-hydroxydopam...

Real-World Patterns of Utilization and Costs Associated with Second-Generation Oral Antipsychotic Medication for the Treatment of Bipolar Disorder: A Literature Review.

Mar 01, 2021

Treatment with second-generation antipsychotics (SGAs) for bipolar disorder, including bipolar I disorder (BD-I), is common. This review evaluated real-world utilization patterns with oral SGAs in the...

Manic-Depressive Cycles in Bipolar Disorder: Clinical and Treatment Implications.

Mar 01, 2021

Cycle patterns of bipolar disorders (BDs) have been previously shown to be associated with clinical characteristics and response to lithium salts. Here, we evaluated the distribution of different type...

Perceived helpfulness of bipolar disorder treatment: Findings from the World Health Organization World Mental Health Surveys.

Mar 01, 2021

To examine patterns and predictors of perceived treatment helpfulness for mania/hypomania and associated depression in the WHO World Mental Health Surveys.Face-to-face interviews with community sample...

Heart-focused breathing and perceptions of burden in Alzheimer's caregivers: An online randomized controlled pilot study.

Mar 01, 2021

Informal caregivers of patients with Alzheimer's disease (AD) often experience high stress and reduced wellbeing and quality of life. HeartMath's Heart Lock-In® technique has been shown to reduce str...

Behavioral disorders caused by nonylphenol and strategies for protection.

Mar 01, 2021

Nonylphenol (NP) is widely used in daily production and life due to its good emulsification. In this review, we discuss toxicology studies that examined behavioral disorders caused by NP, the correspo...

Does psychosocial stress modify the association of fine particulate matter and ozone with cardiovascular health indicators?

Mar 01, 2021

Fine particulate matter (PM) and ozone (O) air pollution can cause abnormal changes in blood pressure (BP), blood glucose and lipids, which are important indicators for cardiovascular health. Psychoso...

Heart-focused breathing and perceptions of burden in Alzheimer's caregivers: An online randomized controlled pilot study.

Mar 01, 2021

Informal caregivers of patients with Alzheimer's disease (AD) often experience high stress and reduced wellbeing and quality of life. HeartMath's Heart Lock-In® technique has been shown to reduce str...

Role of Loneliness Feelings in Dementia And Alzheimer Disease

Feb 26, 2021

Alzheimer's disease and dementia are caused by medical conditions. Age, gender, and other demographic factors also have an impact. Further, these diseases can be due to genes, mild cognitive impairmen...

Impact of COVID-19 on Acute Ischemic Stroke Traits and Outcomes

Feb 26, 2021

COVID-19 is a viral pneumonia with symptoms like high fever and dry cough. The patients also complain about shortness of breath, loss of taste, and smell. It is due to the SARS-CoV-2 virus, which can ...

Revisiting nocturnal heart rate and heart rate variability in insomnia: A polysomnography-based comparison of young self-reported good and poor sleepers.

Feb 25, 2021

Primary insomnia is often considered a disorder of 24-hr hyperarousal. Numerous attempts have been made to investigate nocturnal heart rate (HR) and its variability (HRV) as potential pathophysiologic...

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