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Psychiatry General

Efficacy and safety of lemborexant in adults with insomnia: comparing Japanese and non-Japanese subgroups from the global, phase 3, randomized, double-blind, placebo-controlled SUNRISE 2 study.

Feb 15, 2021

Whether there are racial differences in the efficacy/safety of hypnotics has not been sufficiently investigated. We aimed to evaluate the efficacy/safety of lemborexant 5 mg (LEM5) and 10 mg (LEM10) v...

Primary care provider evaluation and management of insomnia.

Feb 15, 2021

To evaluate the type and extent of information collected from patients with insomnia during their first office encounter for insomnia and the prescribing therapies of primary care providers (PCPs) dur...

Associations of Sleep and Health Functioning with Premature Exit from Work: A Cohort Study with a Methodological Emphasis.

Feb 15, 2021

Sleep and functioning are associated with a risk of early workforce exit. However, patterns of change in sleep and functioning through time have not been investigated using person-oriented approaches ...

Deficits in executive functions but not in decision making under risk in individuals with problematic social-network use.

Feb 15, 2021

The tendency to strive for immediate gratification by neglecting potential negative long-term outcomes characterizes addictive behaviors, such as substance use or gaming disorder. Problematic social-n...

Characterizing the building blocks of Problematic Use of the Internet (PUI): The role of obsessional impulses and impulsivity traits among Italian young adults.

Feb 15, 2021

Problematic Use of the Internet (PUI) is a considerable issue of the modern era, but its risk factors are still poorly understood. Impulsivity and obsessive-compulsive symptoms have been associated wi...

Carfentanil - from an animal anesthetic to a deadly illicit drug.

Feb 15, 2021

The use of novel synthetic opioids as recreational drugs has become a public health concern as they are implicated in numerous fatal intoxications across the world. Synthetic opioids have played a maj...

Correlation between depression and quality of life in patients with Parkinson's disease.

Feb 15, 2021

To understand the distribution of Parkinson's disease questionnaire-39 (PDQ-39) scores in Parkinson's disease (PD) patients with or without depression, and to analyze the factors that influence the qu...

Dysregulation of phospholipase and cyclooxygenase expression is involved in Schizophrenia.

Feb 15, 2021

Schizophrenia (SZ) is a severe mental disease with highly heterogeneous clinical manifestations and pathological mechanisms. Schizophrenia is linked to abnormalities in cell membrane phospholipids and...

Carfentanil - from an animal anesthetic to a deadly illicit drug.

Feb 15, 2021

The use of novel synthetic opioids as recreational drugs has become a public health concern as they are implicated in numerous fatal intoxications across the world. Synthetic opioids have played a maj...

Sleep quality trajectories from head and neck cancer diagnosis to six months after treatment.

Feb 15, 2021

Patients with head and neck cancer (HNC) often report disturbances in their sleep quality, impairing their quality of life. This study aims to examine the trajectories of sleep quality from diagnosis ...

Decision-making in single and multiple-screen CCTV surveillance.

Feb 15, 2021

One task of CCTV operation is to decide whether footage shown in videos depicts criminal behaviour, or allows a viewer to predict its occurrence. An increasing prevalence of cameras in the world, mean...

Correlation between depression and quality of life in patients with Parkinson's disease.

Feb 15, 2021

To understand the distribution of Parkinson's disease questionnaire-39 (PDQ-39) scores in Parkinson's disease (PD) patients with or without depression, and to analyze the factors that influence the qu...

Chronic antipsychotic treatment exerts limited effects on the mania-like behavior of dopamine transporter knockdown mice.

Feb 15, 2021

Bipolar disorder is a life-threatening disorder linked to dopamine transporter (DAT) polymorphisms, with reduced DAT levels seen in positron emission tomography and postmortem brains.The purpose of th...

A retrospective study of pituitary-thyroid interaction in patients with first-episode of bipolar disorder type I in Mania State.

Feb 15, 2021

Bipolar disorder (BD)-mania is related to the dysfunction of anterior pituitary gland, but the pituitary-thyroid interaction on the acute stage of BD has been controversial. In order to rule out the e...

Using mitochondrial respiration inhibitors to design a novel model of bipolar disorder-like phenotype with construct, face and predictive validity.

Feb 15, 2021

We mimicked mild mitochondrial-distress robustly reported in bipolar-disorder (BD) by chronic exposure to uniquely low doses of inhibitors of mitochondrial-respiration complexes in vitro and in vivo. ...

Sleep quality trajectories from head and neck cancer diagnosis to six months after treatment.

Feb 15, 2021

Patients with head and neck cancer (HNC) often report disturbances in their sleep quality, impairing their quality of life. This study aims to examine the trajectories of sleep quality from diagnosis ...

Decision-making in single and multiple-screen CCTV surveillance.

Feb 15, 2021

One task of CCTV operation is to decide whether footage shown in videos depicts criminal behaviour, or allows a viewer to predict its occurrence. An increasing prevalence of cameras in the world, mean...

Correlation between depression and quality of life in patients with Parkinson's disease.

Feb 15, 2021

To understand the distribution of Parkinson's disease questionnaire-39 (PDQ-39) scores in Parkinson's disease (PD) patients with or without depression, and to analyze the factors that influence the qu...

Shared breastfeeding & other early multiple sclerosis risk factors: A case-control study.

Feb 15, 2021

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease. Etiology is thought to be multifactorial with genetic and environmental factors interplay. Our objective in this study is to evalu...

3D Virtual Planning For Rhinoplasty Using a Free Add-On For Open-Source Software.

Feb 15, 2021

Rhinoplasty is one of the most frequent aesthetic surgeries; the procedure can be challenging for inexperienced surgeons, and positive outcomes depend on good communication with the patient, proper pl...

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