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Psychiatry General

Contribution of coding/non-coding variants in NUS1 to late-onset sporadic Parkinson's disease.

Feb 08, 2021

A recent study reported that rare variants in NUS1 were associated with Parkinson's disease (PD). We aimed to assess the relative contribution of rare and common coding/non-coding variants of NUS1 to ...

MiRNA -483-5p as a Potential Noninvasive Biomarker for Early Detection of Alzheimer's Disease.

Feb 08, 2021

Alzheimer's disease (AD) is an irreversible, progressive neurodegenerative disease that accounts for 62% of dementia cases in elderly. Early diagnosis of AD is crucial for successful treatment in orde...

[Major depressive episode in college freshmen: prevalence, academic functioning and receipt of treatment].

Feb 08, 2021

Background Little is known about the epidemiology of Major Depressive Episode (mde) in university students. Aim To investigate the prevalence of mde, psychiatric comorbidity, and the association with ...

Association of insomnia with mania in Lebanese patients with bipolar disorder.

Feb 08, 2021

To assess: (1) the association between insomnia experienced at admission, sociodemographic and other patients' characteristics and mania; and (2) the variation of insomnia and mania before and after t...

New Pharmacological Interventions in Bipolar Disorder.

Feb 08, 2021

The biological bases of bipolar disorder include aspects related, among others, to neurohormonal pathways, neurotransmission, signal transduction, regulation of gene expression, oxidative stress, neur...

Serotonin 2A receptor polymorphism rs3803189 mediated by dynamics of default mode network: a potential biomarker for antidepressant early response.

Feb 08, 2021

Serotonin 2A receptors (HTR2A) play a crucial role in the therapeutic response to antidepressant. The activity of serotonergic system could modulate the connectivity of the default mode network (DMN) ...

Responses of people with epilepsy to the COVID-19 pandemic in the time of national lockdown.

Feb 08, 2021

The aim of our study was to gather information on how people with epilepsy (PwE) responded to the COVID-19 pandemic during the national lockdown. An online questionnaire was therefore offered to the v...

The Effect of Lavender Oil on Perioperative Pain, Anxiety, Depression, and Sleep after Microvascular Breast Reconstruction: A Prospective, Single-Blinded, Randomized, Controlled Trial.

Feb 08, 2021

 Psychosocial distress, depression, or anxiety can occur in up to 50% of women after a breast cancer diagnosis and mastectomy. The purpose of this study was to assess the potential benefit of lavend...

Assessing ADHD symptoms in clinical public practice: Is a reliable final diagnosis possible?

Feb 08, 2021

Attention deficit and hyperactivity disorder (ADHD) rates vary between 1% and 20% depending on the type of diagnosis guide used, the test used in the assessment, psychosocial factors, and professional...

ADHD severity as a predictor of cognitive task performance in children with Autism Spectrum Disorder (ASD).

Feb 08, 2021

In recent years, a number of studies have begun to explore the nature of Attention-Deficit/Hyperactivity Disorder (ADHD) in children with Autism Spectrum Disorder (ASD). In this study, we examined the...

Epidemic spreading in a weighted pig trade network.

Feb 08, 2021

The inclusion of edge weights can add valuable insights in the spreading processes within trade networks and may identify factors influencing the final epidemic size. The aim of the study was to evalu...

Evaluation of Opioid Prescription and Consumption Habits Following Endovascular Aortic Aneurysm Repair.

Feb 08, 2021

There has been a dramatic rise in opioid-related deaths over the past decade. Most of the reduction strategies have focused on outpatient use; however, recent studies have demonstrated an association ...

Intraoperative Local Injection of Uterosacral Ligaments with Ropivacaine during Uterine Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Feb 08, 2021

To perform a systematic review and meta-analysis of all randomized controlled trials that examined the efficacy of intraoperative local injection of the uterosacral ligaments with ropivacaine on posto...

Patterns of dispensed opioids after tonsillectomy in children and adolescents in South Carolina, United States, 2010-2017.

Feb 08, 2021

Tonsillectomy (with or without adenoidectomy) is a common pediatric surgical procedure requiring post-operative analgesia. Because of the respiratory depression effects of opioids, clinicians strive t...

Could Polygenic Risk Scores Be Useful in Psychiatry?: A Review.

Feb 08, 2021

Polygenic risk scores (PRS) are predictors of the genetic susceptibility to diseases, calculated for individuals as weighted counts of thousands of risk variants in which the risk variants and their w...

Transcription Regulation & Cocaine Action by Gadd45b

Feb 08, 2021

This research has been done so as to understand the Exposure to drugs of abuse produces robust transcriptional and epigenetic reorganization within brain reward circuits that outlives the direct effec...

Pharmacokinetic Effects of THC in Adolescent Rats

Feb 08, 2021

So this study states that Δ9-tetrahydrocannabinol (THC) is the intoxicating constituent of cannabis and is responsible for the drug’s reinforcing effects. Retrospective human studies suggest that c...

Predicting Diagnosis Change from MDD to BD

Feb 08, 2021

We aimed to develop and validate classification models able to identify individuals at high risk for transition from a diagnosis of depressive disorder to one of bipolar disorder. This retrospective h...

Pcsk5 Activation of in Mouse LHb Causes Depressive-like Behaviors

Feb 08, 2021

The following research has been performed so as to understand how The lateral habenula (LHb)  pulls in a developing interest as a controller of monoaminergic movement which were habitually answered t...

Potential Biomarker for Psychosis Treatment Stratification

Feb 08, 2021

This study states that Schizophrenia and related crazy issues are basic mental issues and among the main sources of worldwide handicap. Antipsychotic drugs are key to their treatment [4, 5]. In any ca...

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