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Sleep Disorders

Hypocretinergic interactions with the serotonergic system regulate REM sleep and cataplexy.

Nov 30, 2020

Loss of muscle tone triggered by emotions is called cataplexy and is the pathognomonic symptom of narcolepsy, which is caused by hypocretin deficiency. Cataplexy is classically considered to be an abn...

Impact of COVID-19 pandemic lockdown on narcolepsy type 1 management.

Nov 30, 2020

Narcolepsy type 1 (NT1) is a chronic rare hypersomnia of central origin requiring a combination of behavioral and pharmacological treatments. During the coronavirus disease 2019 (COVID-19) pandemic, i...

Sleep misestimation among older adults suffering from insomnia with short and normal objective sleep duration and the effects of Cognitive Behaviour Therapy.

Nov 26, 2020

Compare the degree of sleep misestimation in older adults with insomnia presenting with objectively short relative to normal sleep duration, and investigate the differential therapeutic response on sl...

Chronic apnea during REM sleep increases arterial pressure and sympathetic modulation in rats.

Nov 26, 2020

Obstructive sleep apnea can induce hypertension. Apneas in REM may be particularly problematic: they are independently associated with hypertension. We examined the role of sleep stage and awakening o...

Associations of Insomnia Symptoms with Subsequent Health Services Use among Community-Dwelling U.S. Older Adults.

Nov 26, 2020

Determine the association of insomnia symptoms with subsequent health services use, in a representative sample of U.S. older adults.Participants were 4,289 community-dwelling Medicare beneficiaries wh...

Understanding the role of echocardiography in patients with obstructive sleep apnea and right ventricular subclinical myocardial dysfunction - comparison with other conditions affecting RV deformation.

Nov 23, 2020

Despite efforts to treat obstructive sleep apnea syndrome (OSA), the condition remains an important risk factor in the development of cardiovascular disease. Early detection of RV dysfunction with nov...

Vasorelaxant effects of benzodiazepines, non-benzodiazepine sedative-hypnotics, and tandospirone on isolated rat arteries.

Nov 23, 2020

Benzodiazepines (BDZs) and non-BDZ sedative-hypnotics are effective for the management of chronic insomnia; however, they are associated with adverse effects such as headache, dizziness, and palpitati...

Effect of Adenotonsillectomy on Cardiac function in Children Age 5-13 years with Obstructive Sleep Apnea.

Nov 23, 2020

Changes in left ventricular structure and function have been previously described in children with obstructive sleep apnea (OSA). We aimed to determine if these structural and functional cardiac chang...

Ganglion cell layer thickening in patients suffering from Obstructive Sleep Apnea-Hypopnea syndrome with long Mean Apnea-Hypopnea Duration during sleep.

Nov 19, 2020

To study the effects of mean apnea-hypopnea duration (MAD), a useful indicator of blood oxygenation, on peripapillary retinal nerve fiber layer (RNFL), macular ganglion cell to inner plexiform layer...

PAP Adherence and Nasal Resistance: A Randomized Control Trial of CPAP vs CPAP.

Nov 19, 2020

CPAP adherence is often poor in obstructive sleep apnea (OSA) and may be influenced by nasal resistance. CPAP with reduction of expiratory pressure (CPAP) may reduce discomfort in those with high nasa...

Augmentation with Atypical Antipsychotics for Treatment-Resistant Depression.

Nov 19, 2020

Treatment-resistant depression (TRD) is considered a common clinical condition often associated with relevant suicidal ideation and characterized by a severe functional impairment lifetime. Among the ...

Correlation between adenotonsillar microbiome and clinical characteristics of pediatrics with snoring.

Nov 16, 2020

The paired microbiome of adenoids and tonsils in pediatric patients with snoring has rarely been reported, and its correlation with clinical characteristics has not been evaluated till date. The aim o...

Paradigm Shift in Airway Management for Pierre Robin Sequence: Tongue Base Suspension.

Nov 16, 2020

Surgical management of the airway in children with Pierre Robin Sequence (PRS) includes tongue lip adhesion and mandibular distraction. Herein, the authors report the first case of an alternative surg...

Mandibular Advancement Devices for OSA: An Alternative to CPAP?

Nov 12, 2020

Obstructive sleep apnea (OSA) is a prevalent condition causing unrefreshing sleep and excessive daytime sleepiness. It has individual socioeconomic impacts and, through association with increased risk...

Does Ibuprofen Increase Bleed Risk for Pediatric Tonsillectomy?

Nov 12, 2020

To evaluate risk factors for pediatric posttonsillectomy hemorrhage (PTH) and the need for transfusion using a national database.Retrospective cohort study.The study was conducted using the Pediatric ...

The bidirectional association between sleep and physical activity: A 6.9 years longitudinal analysis of 38,601 UK Biobank participants.

Nov 12, 2020

Although physical activity and sleep may influence each other, little is known about the bidirectional association of the two behaviors. Analyses included 38,601 UK Biobank participants (51% female, 5...

Biological rhythms and chronotherapeutics in depression.

Nov 09, 2020

Depressive syndromes are frequent and heterogeneous brain conditions with more than 90% of patients suffering from sleep complaints. Better characterizing this "sleep" domain may allow to both better ...

Adenoidectomy: Inpatient criteria study.

Nov 09, 2020

Current practices for admission for overnight observation after an adenoidectomy alone vary from hospital to hospital, as there are currently no studies that provide evidence for overnight observation...

Quality of life and procrastination in post-H1N1 narcolepsy, sporadic narcolepsy and idiopathic hypersomnia, a Swedish cross-sectional study.

Nov 09, 2020

A cross-sectional study of health-related quality of life (HRQoL), procrastination and the relation to sleepiness, depression and fatigue in post-H1N1 narcolepsy type 1 (NT1), sporadic NT1 and idiopat...

Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea.

Nov 05, 2020

Obstructive sleep apnoea (OSA) is a syndrome characterised by episodes of apnoea (complete cessation of breathing) or hypopnoea (insufficient breathing) during sleep. Classical symptoms of the disease...

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