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Psychiatry General

Uncovering the brain-wide pattern of synaptic input to vasopressin-expressing neurons in the paraventricular nucleus of the hypothalamus.

May 01, 2023

Arginine vasopressin (AVP) is a neuropeptide critical for the mammalian stress response and social behavior. AVP produced in the hypothalamus regulates water osmolality and vasoconstriction in the bod...

Evaluation of Brain-Body Health in Individuals With Common Neuropsychiatric Disorders.

May 01, 2023

Physical health and chronic medical comorbidities are underestimated, inadequately treated, and often overlooked in psychiatry. A multiorgan, systemwide characterization of brain and body health in ne...

Navigating the Gender Gap: Genetic Influences on Depression and Alcohol Consumption

Apr 24, 2023

The following is a summary of “Genetic predisposition to major depressive disorder differentially impacts alcohol consumption and high-risk drinking situations in men and women with alcohol use diso...

Sleep Problems, Suicidal Ideation, and Psychopathology in First-Episode Psychosis.

Apr 24, 2023

Insomnia occurs frequently in the clinical course of schizophrenia. A growing literature has found associations between insomnia, suicidal ideation and behavior, and psychopathology in schizophrenia. ...

Insight into mitochondrial dysfunction mediated by clozapine-induced inhibition of PGRMC1 in PC12 cells.

Apr 24, 2023

Clozapine is usually considered as the last resort for treatment-resistant schizophrenia (TRS). However, it shows limited efficacy in cognition improvement. Moreover, the metabolic side effects induce...

Catatonia and ECT across the lifespan.

Apr 24, 2023

Electroconvulsive therapy (ECT) is a safe and effective treatment for catatonia with high response rates. Although empirical data suggest that tolerability and efficacy are at least as good as in adul...

Behavioral Activation Disseminated by Non-Mental Health Professionals, Paraprofessionals, and Peers: A Systematic Review.

Apr 24, 2023

There is a striking disparity between the number of individuals with significant mental health concerns and those who are able to access care globally. One promising solution to expanding the mental h...

Atypical antipsychotic-induced mania: A systematic review and meta-analysis.

Apr 24, 2023

The possibility of atypical antipsychotics (AA) to induce manic symptoms has been raised by several articles. The objective of this study was to describe whether exposure to AA may induce mania in moo...

Decreased serum allopregnanolone and progesterone levels in male patients with bipolar disorder and their effects on cognitive functions.

Apr 24, 2023

The progression of bipolar disorder (BD) is characterized by recurrent episodes of depression, mania, and hypomania, thus affecting the daily functionality of individuals. Previous studies have shown ...

Developing Transdiagnostic Internalizing Disorder Prognostic Indices for Outpatient Cognitive Behavioral Therapy.

Apr 24, 2023

A growing literature is devoted to understanding and predicting heterogeneity in response to cognitive behavioral therapy (CBT), including using supervised machine learning to develop prognostic model...

Examining Safety Behavior Subtypes Across Distinct Social Contexts in Social Anxiety Disorder and Major Depression.

Apr 24, 2023

People with social anxiety disorder (SAD) use different types of safety behaviors that have been classified as avoidance vs. impression management. The current study investigated differences in safety...

Associations Between Abstinence Plans and Spouse Support & Conflict Over Smoking Cigarettes

Apr 21, 2023

The following is a summary of "Interactive associations between abstinence plans and romantic partner conflict and support with cigarette smoking," published in the February 2023 issue of  Drug and A...

Nicotine Dependence Assessment: The Roswell eND Scale for E-Cigarette Users

Apr 20, 2023

The following is a summary of "Roswell eND scale: Brief, valid assessment of nicotine dependence adults seeking to discontinue e-cigarette use," published in the February 2023 issue of Drug and Alcoho...

Transitions in Care for Patients with Substance Use Disorders Between Hospital and Community Settings

Apr 19, 2023

The following is a summary of “Transitions in care between hospital and community settings for individuals with a substance use disorder: A systematic review,” published in the February 2023 issue...

Uncovering the Validity of Brief Self-Report Measures for Substance Use Disorders

Apr 18, 2023

The following is a summary of "A systematic review of brief, freely accessible, and valid self-report measures for substance use disorders and treatment," published in the February 2023 issue of Psych...

Pharmacologic Management of Cognitive Disengagement Syndrome (CDS) and Implications for Attention-Deficit/Hyperactivity Disorder (ADHD) Treatment: Emerging Treatments and Recommendations for Future Research.

Apr 17, 2023

Although the study of cognitive disengagement syndrome (CDS; previously called sluggish cognitive tempo) first emerged in the 1980s, very little is known about treating CDS or its impact on evidence-b...

Prevalence and Correlates of Mental Disorders in Children Aged 9 and 10 Years: Results From the ABCD Study.

Apr 17, 2023

To estimate the prevalence of current DSM-5 disorders in children, ages 9 to 10 years, and their associations with sociodemographic and physical characteristics.In this analysis of the Adolescent Brai...

Exploring the mediation of DNA methylation across the epigenome between childhood adversity and First Episode of Psychosis-findings from the EU-GEI study.

Apr 17, 2023

Studies conducted in psychotic disorders have shown that DNA-methylation (DNAm) is sensitive to the impact of Childhood Adversity (CA). However, whether it mediates the association between CA and psyc...

Cerebral Asymmetry in Bipolar Disorders: A Scoping Review.

Apr 17, 2023

Current brain stimulation protocols for patients with bipolar disorders propose brain stimulation according to a model of opposing cerebral dominance in mania and bipolar depression by stimulating the...

Evaluation of health-related quality of life and its domains in pediatric patients with cancer.

Apr 17, 2023

Health-related quality of life has emerged as a significant component in pediatric oncology research during the last several decades. Measures of health-related quality of life provide a thorough asse...

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