Mar 19, 2020

Alzheimer's disease is the world's most common neurodegenerative disorder. It is associated with neuroinflammation involving activation of microglia by β-amyloid (Aβ) deposits. Based on previous stu...

Mar 19, 2020

Identifying the interplay between socioeconomic markers (education and financial resources) and polygenetic predisposition influencing the time of dementia and the diagnosis of clinical Alzheimer's di...

Mar 19, 2020

The first draft human mitochondrial DNA (mtDNA) sequence was published in 1981, paving the way for two decades of discovery linking mtDNA variation with human disease. Severe pathogenic mutations caus...

Mar 19, 2020

Mild encephalitis with reversible splenial lesion is a rare clinic-radiological entity presenting with neurological and neuropsychiatric symptoms associated with cerebral lesion/s. Delirious mania is ...

Mar 19, 2020

Psychiatric and neurocognitive symptoms due to hypercortisolism were already described by Harvey Cushing in his original paper on patients with Cushing's syndrome (CS). Nowadays, it is well known that...

Mar 19, 2020

Previous case reports showed that delirious mania could be one of the many neuropsychiatric presentations of Anti-N-methyl-d-aspartate receptor encephalitis (ANMDARE).To evaluate the frequency of deli...

Mar 19, 2020

To study predictors of the number of electroconvulsive therapy (ECT) sessions required for symptom remission in psychiatric patients.We conducted chart reviews for 95 patients whose condition remitted...

Mar 19, 2020

The metabolic syndrome (MS) is highly prevalent among patients with bipolar disorder (BD), and may affect progression, functioning, and comorbid conditions in BD. The aim of this study was to investig...

Mar 19, 2020

Two novel bipolar deep-blue fluorescent emitters, IP-PPI and IP-DPPI featuring different lengths of phenyl bridge, were designed and synthesized, in which imidazo[1,2-a]pyridine (IP) and phenanthroimi...

Mar 19, 2020

Heterogeneity in major depressive disorder (MDD) is well recognized but not well understood. Core depressive features are reward and emotional symptoms, which reflect dysfunctions in the positive vale...

Mar 19, 2020

Despite the well-known association between anxiety and risk-avoidant decision making, it is unclear how pathological anxiety biases risk learning. We propose a Bayesian inference model with bias param...

Mar 19, 2020

Fatigue is a common and disabling symptom amongst people with multiple sclerosis, however it has not been compared across the central nervous system (CNS) inflammatory diseases associated with aquapor...

Mar 19, 2020

Despite the fact that negative mood and executive dysfunction are common after risk-reducing salpingo-oophorectomy (RRSO), occurring in up to a third of women, little is known about risk factors predi...

Mar 19, 2020

Participation, defined as 'involvement in life situations' according to the World Health Organisation, is a well-recognized concept and critical indicator of quality of life. In addition it has become...

Mar 19, 2020

The interest in reef manta rays (Mobula alfredi) from the scientific community is growing in reaction to the major decline of populations around the world. Studies have highlighted the need to further...

Mar 19, 2020

Increases in acute hepatitis C virus (HCV) incidence may be a result of the rising prevalence of injection-drug use and the opioid epidemic. Amongst persons who inject drugs, sharing of needles/syring...

Mar 19, 2020

In patients at low clinical probability of acute aortic syndromes (AASs), decision on advanced aortic imaging is cumbersome. Integration of the aortic dissection detection risk score (ADD-RS) with D-d...

Mar 19, 2020

The benefit of a perianal block as an adjunct to general or regional anaesthesia is debated. This RCT aimed to compare pain at 24 h and up to 14 days after proctological surgery in patients with a...

Mar 19, 2020

An increasing trend in opioid consumption has been observed worldwide in last decades. However, data related to opioid utilization in hospital settings is scarce. The aim of this study was to determin...

Mar 19, 2020

This study aimed at identifying characteristics of individuals who are most likely to benefit from long-term opioid therapy in terms of reduction in pain severity and improved mental health-related qu...