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Psychiatry General

Effects of BXSMD on ESR1 and ESR2 expression in CSD female mice.

Jul 31, 2023

Due to the rapid pace of modern society, chronic insomnia has become universal phenomenon. In China, Banxia Shumi Decoction (BXSMD) has been used in treating chronic insomnia for thousands of years, b...

Longitudinal Associations between Perceived Discrimination and Suicidality in Youth.

Jul 31, 2023

Research among adults reveals robust associations between discrimination and suicidality. The relationship between discrimination and suicidality is understudied in youth. Participants in the Adolesce...

Sex and gender differences in healthcare utilisation trajectories: a cohort study among Quebec workers living with chronic pain.

Jul 31, 2023

Chronic pain (CP) is a poorly recognised and frequently inadequately treated condition affecting one in five adults. Reflecting on sociodemographic disparities as barriers to CP care in Canada was rec...

A Case of Delirious Mania Treated with Electroconvulsive Therapy.

Jul 31, 2023

(1) Background: Delirious mania is a neuropsychiatric condition characterized by the rapid onset of delirium, psychosis, and mania. Due to the presence of catatonic signs and symptoms, some authors co...

Exploring the Molecular Targets for the Antidepressant and Antisuicidal Effects of Ketamine Enantiomers by Using Network Pharmacology and Molecular Docking.

Jul 31, 2023

Ketamine, a racemic mixture of esketamine (S-ketamine) and arketamine (R-ketamine), has received particular attention for its rapid antidepressant and antisuicidal effects. NMDA receptor inhibition ha...

The Economic Burden of Adults with Major Depressive Disorder in the United States (2019).

Jul 31, 2023

Previous societal burden estimations for major depressive disorder (MDD) often fail to account for several hidden cost components. This study provides a comprehensive evaluation of societal costs for ...

Perceived cognitive impairment is related to internalizing psychopathology but unrelated to objective cognitive performance among nongeriatric adults presenting for outpatient neuropsychological evaluation.

Jul 31, 2023

This study investigated the relationship between perceived cognitive impairment, objective cognitive performance, and intrapersonal variables thought to influence ratings of perceived cognitive impai...

Differential characteristics of bipolar I and II disorders: a retrospective, cross-sectional evaluation of clinical features, illness course, and response to treatment.

Jul 17, 2023

The distinction between bipolar I and bipolar II disorder and its treatment implications have been a matter of ongoing debate. The aim of this study was to examine differences between patients with bi...

Differential characteristics of bipolar I and II disorders: a retrospective, cross-sectional evaluation of clinical features, illness course, and response to treatment.

Jul 17, 2023

The distinction between bipolar I and bipolar II disorder and its treatment implications have been a matter of ongoing debate. The aim of this study was to examine differences between patients with bi...

Clinical experience of electroconvulsive therapy with anaesthetic and muscle relaxant at the Clínica Universidad de La Sabana: 2009-2017.

Jul 17, 2023

Electroconvulsive therapy is an effective and safe procedure, which is indicated mainly in patients with both unipolar and bipolar depressive episodes, mania and schizophrenia, when they do not respon...

Clinical feasibility of radiofrequency ablation using novel adjustable separable electrodes with a multipurpose needle for treating small hepatocellular carcinomas: a prospective single center study.

Jul 17, 2023

The novel separable clustered electrode system with two adjustable active tips (ICAEs) and a fine multipurpose needle (MPN) for temperature monitoring and adjuvant agent injection was developed and v...

A prospective investigation of impacts of comorbid attention deficit hyperactivity disorder (ADHD) on clinical features and long-term treatment response in adult patients with obsessive-compulsive disorder (OCD).

Jul 17, 2023

A close association between obsessive-compulsive disorder (OCD) and attention-deficit/hyperactivity disorder (ADHD) in children and adolescents has been investigated in previous studies. However, few ...

Adverse effects of 21 antidepressants on sleep during acute-phase treatment in major depressive disorder: A systemic review and dose-effect network meta-analysis.

Jul 10, 2023

Sleep-related adverse effects during acute treatment with antidepressants undermine compliance and impede remission. We aimed to address subtypes of sleep-related adverse effects and depict the relati...

Adverse effects of 21 antidepressants on sleep during acute-phase treatment in major depressive disorder: A systemic review and dose-effect network meta-analysis.

Jul 10, 2023

Sleep-related adverse effects during acute treatment with antidepressants undermine compliance and impede remission. We aimed to address subtypes of sleep-related adverse effects and depict the relati...

Inflammatory subgroups of schizophrenia and their association with brain structure: A semi-supervised machine learning examination of heterogeneity.

Jul 10, 2023

Immune system dysfunction is hypothesised to contribute to structural brain changes through aberrant synaptic pruning in schizophrenia. However, evidence is mixed and there is a lack of evidence of in...

Mental health literacy and relational health literacy among college students.

Jul 10, 2023

The aim of the present study was to examine MHL and RHL in a sample of college students in the United States, and to explore linkages among literacies and related constructs. Participants were 169 (...

Non-Psychosis Symptoms of Clozapine Withdrawal: a Systematic Review.

Jul 10, 2023

Clozapine is a potent antipsychotic medication with a complex receptor profile. It is reserved for treatment-resistant schizophrenia. We systematically reviewed studies of non-psychosis symptoms of cl...

Determinants and mediating mechanisms of quality of life and disease-specific symptoms among thyroid cancer patients: the design of the WaTCh study.

Jul 10, 2023

Thyroid cancer (TC) patients are understudied but appear to be at risk for poor physical and psychosocial outcomes. Knowledge of the course and determinants of these deteriorated outcomes is lacking. ...

Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment.

Jul 03, 2023

Weight gain is a common harmful side effect of atypical antipsychotics used for schizophrenia treatment. Conversely, treatment with the novel phosphodiesterase-10A (PDE10A) inhibitor MK-8189 in clinic...

The self, neuroscience and psychosis study: Testing a neurophenomenological model of the onset of psychosis.

Jul 03, 2023

Basic self disturbance is a putative core vulnerability marker of schizophrenia spectrum disorders. The primary aims of the Self, Neuroscience and Psychosis (SNAP) study are to: (1) empirically test a...

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